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多节段颈椎后纵韧带骨化症患者前路可控性前移位融合与后路单开门椎管扩大成形术的疗效比较:一项前瞻性、随机对照研究,至少随访 1 年。

Comparison of Anterior Controllable Antedisplacement and Fusion With Posterior Laminoplasty in the Treatment of Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Prospective, Randomized, and Control Study With at Least 1-Year Follow Up.

机构信息

Spine Center, Department of Orthopaedics, Changzheng Hospital, Second Military Medical University, Shanghai, China.

出版信息

Spine (Phila Pa 1976). 2020 Aug 15;45(16):1091-1101. doi: 10.1097/BRS.0000000000003462.

Abstract

STUDY DESIGN

A prospective, randomized, controlled study.

OBJECTIVE

To compare anterior controllable antidisplacement and fusion (ACAF) with laminoplasty in the treatment of multilevel ossification of the posterior longitudinal ligament (OPLL), and evaluate the efficacy and safety of this procedure.

SUMMARY OF BACKGROUND DATA

The optimal approach for the treatment of OPLL still remains controversial. Both anterior and posterior approaches have their advantages and disadvantages.

METHODS

Between September 2016 and April 2018, a total of 80 patients with multilevel OPLL were randomized in a 1:1 ratio to ACAF group and laminoplasty group. All patients were followed up at least 1 year. Clinical and radiological results were compared between ACAF group and laminoplasty group.

RESULTS

ACAF took a longer operation time. C5 palsy and axial pain occurred more commonly in laminoplasty group, whereas dysphagia and hoarseness appeared easily in ACAF group. At 1-year follow-up, the final Japanese Orthopedic Association (JOA) score and recovery rate were significant higher in ACAF group than those in laminoplasty group, when occupying rate (OR) was not less than 60%, or K-line was negative. ACAF was also good at preservation of cervical lordosis and sagittal balance, but range of movement of cervical spine in both groups decreased significantly.

CONCLUSION

Generally speaking, ACAF is a safe and effective alternative for multilevel OPLL. Compared with laminoplasty, ACAF is more effective in the cases when OR is not less than 60%, or K-line is negative.

LEVEL OF EVIDENCE

摘要

研究设计

前瞻性、随机、对照研究。

目的

比较前路可控式抗位移融合术(ACAF)与椎板成形术治疗多节段后纵韧带骨化症(OPLL)的疗效,并评估该术式的安全性。

背景资料总结

OPLL 的最佳治疗方法仍存在争议。前路和后路入路都有其优缺点。

方法

2016 年 9 月至 2018 年 4 月,80 例多节段 OPLL 患者按 1:1 比例随机分为 ACAF 组和椎板成形术组。所有患者均至少随访 1 年。比较 ACAF 组与椎板成形术组的临床和影像学结果。

结果

ACAF 手术时间较长。椎板成形术组更常发生 C5 神经麻痹和轴向疼痛,而 ACAF 组更易出现吞咽困难和声音嘶哑。在 1 年随访时,当占有率(OR)≥60%或 K 线为阴性时,ACAF 组的最终日本矫形协会(JOA)评分和恢复率明显高于椎板成形术组。ACAF 还能更好地保持颈椎生理曲度和矢状位平衡,但两组颈椎活动度均明显下降。

结论

一般来说,ACAF 是治疗多节段 OPLL 的一种安全有效的方法。与椎板成形术相比,ACAF 在 OR≥60%或 K 线为阴性的病例中更有效。

证据等级

2 级。

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