Department of Orthopaedic Surgery, Hanyang University College of Medicine, Seoul, Republic of Korea.
Spine (Phila Pa 1976). 2020 Jul 15;45(14):E856-E863. doi: 10.1097/BRS.0000000000003445.
Population-based study. From 2008 to 2017, data from the national database of the Korean Health Insurance Review & Assessment Service were analyzed. The national insurance system and all medical expense bill data of the entire population are included in the database.
The aim of this study was to elucidate the incidence and management trends of metastatic spinal tumors in South Korea.
The spine is the most common location of bone metastases. However, population-based studies in this topic are limited.
The International Classification of Disease, 10th revision, medical behavior, and examination codes were used to identify the incidence and management trends of metastatic spinal tumors. The Cochran-Armitage trend test was used in statistical analysis.
Overall, 38,007 patients (average age, 61 years) diagnosed with metastatic spinal tumors were analyzed. Metastatic tumors were most common in patients in their 60s (25.7%). The 10-year incidence of spinal metastases in South Korea was 6.68 cases per 100,000 population. The age-adjusted incidence per 100,000 population decreased from 8.16 cases in 2008 to 6.18 in 2017 (P = 0.03). Sex-adjusted incidence rates in men increased from 8.60 per 100,000 persons in 2008 to 8.70 in 2017 (P < 0.001); those of women decreased from 8.20 per 100,000 persons in 2008 to 4.15 in 2017 (P < 0.05). The most common primary tumor site was the lung (26.9%), followed by the breast (16.9%), prostate (10.8%), and liver (8.1%). Radiation therapy was constant at about 3500 cases per annum (P = 0.62); surgical treatment increased from 1158 to 1382 cases (P < 0.001). Resection and instrumentation surgeries increased significantly (P < 0.001), whereas cementation decreased continuously. Total healthcare costs increased significantly from $19,925,296 in 2008 to $30,268,217 in 2017 (P < 0.001).
The incidence of metastatic spinal tumors decreased in South Korea. Resection and instrumentation procedures increased, and total healthcare costs increased rapidly.
基于人群的研究。2008 年至 2017 年，分析了韩国健康保险审查与评估服务国家数据库的数据。该数据库包含国家保险系统和全体人口的所有医疗费用账单数据。
本研究旨在阐明韩国转移性脊柱肿瘤的发病率和管理趋势。
脊柱是骨转移最常见的部位。然而，在该主题方面，基于人群的研究有限。
使用国际疾病分类第 10 版、医疗行为和检查代码来确定转移性脊柱肿瘤的发病率和管理趋势。使用 Cochran-Armitage 趋势检验进行统计分析。
共分析了 38007 例（平均年龄 61 岁）诊断为转移性脊柱肿瘤的患者。转移性肿瘤在 60 多岁的患者中最为常见（25.7%）。韩国脊柱转移瘤的 10 年发病率为每 10 万人中有 6.68 例。经年龄调整后，每 10 万人中的发病率从 2008 年的 8.16 例下降到 2017 年的 6.18 例（P=0.03）。男性的发病率从 2008 年的每 10 万人 8.60 例增加到 2017 年的 8.70 例（P<0.001）；女性的发病率从 2008 年的每 10 万人 8.20 例下降到 2017 年的 4.15 例（P<0.05）。最常见的原发性肿瘤部位是肺部（26.9%），其次是乳腺（16.9%）、前列腺（10.8%）和肝脏（8.1%）。放射治疗每年约为 3500 例（P=0.62）保持稳定；手术治疗从 1158 例增加到 1382 例（P<0.001）。切除术和器械手术显著增加（P<0.001），而骨水泥固定术则持续减少。总医疗保健费用从 2008 年的 19925296 美元显著增加到 2017 年的 30268217 美元（P<0.001）。
韩国转移性脊柱肿瘤的发病率下降。切除术和器械手术增加，总医疗保健费用迅速增加。
3 级
