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本文引用的文献

1
Using Death Certificates to Explore Changes in Alcohol-Related Mortality in the United States, 1999 to 2017.利用死亡证明探讨 1999 年至 2017 年美国与酒精相关的死亡率变化
Alcohol Clin Exp Res. 2020 Jan;44(1):178-187. doi: 10.1111/acer.14239. Epub 2020 Jan 7.
2
Tributyrin Inhibits Ethanol-Induced Epigenetic Repression of CPT-1A and Attenuates Hepatic Steatosis and Injury.丁三醇抑制乙醇诱导的 CPT-1A 表观遗传抑制并减轻肝脂肪变性和损伤。
Cell Mol Gastroenterol Hepatol. 2020;9(4):569-585. doi: 10.1016/j.jcmgh.2019.10.005. Epub 2019 Oct 22.
3
The gut-liver axis in liver disease: Pathophysiological basis for therapy.肝脏疾病中的肠-肝轴：治疗的病理生理学基础。
J Hepatol. 2020 Mar;72(3):558-577. doi: 10.1016/j.jhep.2019.10.003. Epub 2019 Oct 14.
4
Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.酒精性肝炎中 HNF4alpha 依赖性基因表达缺陷作为肝细胞衰竭的驱动因素。
Nat Commun. 2019 Jul 16;10(1):3126. doi: 10.1038/s41467-019-11004-3.
5
Current trials and novel therapeutic targets for alcoholic hepatitis.目前治疗酒精性肝炎的试验和新的治疗靶点。
J Hepatol. 2019 Feb;70(2):305-313. doi: 10.1016/j.jhep.2018.10.026.
6
Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual Data From Controlled Trials.皮质类固醇与己酮可可碱或安慰剂相比可降低重症酒精性肝炎患者 28 天内的死亡率：来自对照试验的个体数据的荟萃分析。
Gastroenterology. 2018 Aug;155(2):458-468.e8. doi: 10.1053/j.gastro.2018.05.011. Epub 2018 May 5.
7
Prophylactic tributyrin treatment mitigates chronic-binge ethanol-induced intestinal barrier and liver injury.预防性三丁酸甘油酯治疗可减轻慢性暴饮乙醇诱导的肠道屏障和肝损伤。
J Gastroenterol Hepatol. 2017 Sep;32(9):1587-1597. doi: 10.1111/jgh.13731.
8
Binge ethanol-induced HDAC3 down-regulates Cpt1α expression leading to hepatic steatosis and injury. binge 乙醇诱导的 HDAC3 下调 Cpt1α 的表达，导致肝脂肪变性和损伤。
Alcohol Clin Exp Res. 2013 Nov;37(11):1920-9. doi: 10.1111/acer.12172. Epub 2013 Jul 26.
9
Metagenomic analyses of alcohol induced pathogenic alterations in the intestinal microbiome and the effect of Lactobacillus rhamnosus GG treatment.酒精诱导的肠道微生物组病理改变的宏基因组学分析及鼠李糖乳杆菌 GG 治疗的效果。
PLoS One. 2013;8(1):e53028. doi: 10.1371/journal.pone.0053028. Epub 2013 Jan 9.
10
Epigenetic regulation in alcoholic liver disease.酒精性肝病中的表观遗传调控。
World J Gastroenterol. 2011 May 28;17(20):2456-64. doi: 10.3748/wjg.v17.i20.2456.

Targeting Epigenetic Mechanisms to Alleviate Alcoholic Steatosis.

作者信息

Mandrekar Pranoti

机构信息

Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.

出版信息

Cell Mol Gastroenterol Hepatol. 2020;9(4):713-714. doi: 10.1016/j.jcmgh.2020.01.013. Epub 2020 Feb 22.

DOI:10.1016/j.jcmgh.2020.01.013
PMID:32097606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7212487/
Abstract
摘要