Marks W A, Bodensteiner J B, Bobele G B, Hamza M, Wilson D A
Department of Neurology, University of Oklahoma Health Sciences Center, Oklahoma City.
J Child Neurol. 1988 Jul;3(3):205-13. doi: 10.1177/088307388800300311.
Parainflammatory leukoencephalomyelitis is a broad term used to include the spectrum of disorders that affect the central nervous system following infection, immunization, or other noxious stimuli. There is a wide range of clinical and pathologic severity, ranging from acute cerebellar ataxia to acute hemorrhagic leukoencephalopathy. With the improved survival of these patients, magnetic resonance imaging provides a window to the pathologic process, which can aid in the long-term management of these patients. Although lesions of the brainstem and spinal cord correlate well to clinical symptoms, multiple cortical lesions may be present without specific localizing signs. The distribution of magnetic resonance lesions is different from that commonly seen in multiple sclerosis. In some cases, prolonged immunosuppression may be required to prevent recrudescence of the inflammatory response.
副炎性白质脑脊髓炎是一个广义术语，用于涵盖感染、免疫接种或其他有害刺激后影响中枢神经系统的一系列病症。临床和病理严重程度范围广泛，从急性小脑性共济失调到急性出血性白质脑病。随着这些患者生存率的提高，磁共振成像为病理过程提供了一个窗口，有助于对这些患者进行长期管理。尽管脑干和脊髓病变与临床症状密切相关，但可能存在多个皮质病变而无特定定位体征。磁共振病变的分布与多发性硬化症中常见的不同。在某些情况下，可能需要长期免疫抑制以防止炎症反应复发。
