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肌肉萎缩症患者的定时浸没呼气测量

Timed immersion expiration measures in patients with muscular dystrophies.

作者信息

Voos Mariana Callil, Goya Priscila Santos Albuquerque, de Freitas Bruna Leal, Pires Aline Moço Teixeira, Favero Francis Meire, Caromano Fátima Aparecida

机构信息

1Physical Therapy, Speech Therapy and Occupational Therapy Department. Faculty of Medicine, University of São Paulo, Rua Cipotânea 51, São Paulo, SP 05360-000 Brazil.

2Department of Neurology and Neurosurgery, Faculty of Medicine, Federal University of São Paulo, São Paulo, SP Brazil.

出版信息

Arch Physiother. 2020 Feb 18;10:4. doi: 10.1186/s40945-020-0074-3. eCollection 2020.

DOI:10.1186/s40945-020-0074-3
PMID:32099666
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7027248/
Abstract

INTRODUCTION

Muscular dystrophies (MD) cause muscle weakness, affecting motor and respiratory functions. Aquatic activities maintain strength and ventilatory function and may require immersion expiration control.

OBJECTIVES

(1) To describe the evolution of timed immersion expiration in patients with MD in one-year follow-up. (2) to describe motor and respiratory outcomes in one-year follow-up. (3) to investigate possible relationships between timed immersion expiration and age, motor and respiratory functions.

METHOD

Fifty-seven patients with MD (12-35 years, Vignos scale 2-8) were evaluated twice, with one-year interval. Immersion expiration control was timed with a chronometer. Motor function was assessed by Motor Function Measure. The respiratory function was evaluated by spirometry. Analysis of variance compared assessments and Pearson tests investigated relationships between variables and age.

RESULTS

Motor and respiratory functions decreased ( < 0.001) but timed immersion expiration was maintained. Timed immersion expiration was not correlated to motor and respiratory functions.

CONCLUSION

As patients maintained timed immersion expiration in the one-year follow-up, aquatic therapy might be a facilitator for people with MD.

摘要

引言

肌肉萎缩症(MD)会导致肌肉无力,影响运动和呼吸功能。水上活动可维持力量和通气功能,可能需要进行浸没呼气控制。

目的

(1)描述肌肉萎缩症患者在一年随访中定时浸没呼气的变化情况。(2)描述一年随访中的运动和呼吸结果。(3)研究定时浸没呼气与年龄、运动和呼吸功能之间的可能关系。

方法

对57例肌肉萎缩症患者(年龄12 - 35岁,Vignos量表评分为2 - 8)进行了两次评估,间隔一年。使用秒表记录浸没呼气控制时间。通过运动功能测量评估运动功能。通过肺活量测定评估呼吸功能。方差分析比较评估结果,Pearson检验研究变量与年龄之间的关系。

结果

运动和呼吸功能下降(<0.001),但定时浸没呼气得以维持。定时浸没呼气与运动和呼吸功能无关。

结论

由于患者在一年随访中维持了定时浸没呼气,水上疗法可能对肌肉萎缩症患者有益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c8a/7027248/af3de511f2d1/40945_2020_74_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c8a/7027248/7e6d2dba6a63/40945_2020_74_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c8a/7027248/ff53e1645192/40945_2020_74_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c8a/7027248/af3de511f2d1/40945_2020_74_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c8a/7027248/7e6d2dba6a63/40945_2020_74_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c8a/7027248/ff53e1645192/40945_2020_74_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c8a/7027248/af3de511f2d1/40945_2020_74_Fig3_HTML.jpg

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J Exerc Rehabil. 2018 Oct 31;14(5):877-882. doi: 10.12965/jer.1836408.204. eCollection 2018 Oct.
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Corticosteroids in Duchenne muscular dystrophy: impact on the motor function measure sensitivity to change and implications for clinical trials.Duchenne 型肌营养不良症中的皮质类固醇:对运动功能测量变化敏感性的影响及其对临床试验的意义。
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Patients with Duchenne and Becker muscular dystrophies are not more asymmetrical than healthy controls on timed performance of upper limb tasks.
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