Rapp Teresa L, DeForest Cole A
Department of Chemical Engineering, University of Washington, 3781 Okanogan Lane NE, Seattle, WA, 98195, USA.
Department of Bioengineering, University of Washington, 3720 15th Ave NE, Seattle, WA, 98105, USA.
Adv Healthc Mater. 2020 Apr;9(7):e1901553. doi: 10.1002/adhm.201901553. Epub 2020 Feb 25.
Photoresponsive materials have been widely used in vitro for controlled therapeutic delivery and to direct 4D cell fate. Extension of the approaches into a bodily setting requires use of low-energy, long-wavelength light that penetrates deeper into and through complex tissue. This review details recent reports of photoactive small molecules and proteins that absorb visible and/or near-infrared light, opening the door to exciting new applications in multiplexed and in vivo regulation.
光响应材料已在体外广泛用于可控治疗递送和引导4D细胞命运。将这些方法扩展到体内环境需要使用低能量、长波长的光，这种光能够更深地穿透复杂组织。本综述详细介绍了吸收可见光和/或近红外光的光活性小分子和蛋白质的最新报道，为多重和体内调节中的激动人心的新应用打开了大门。
