从尼泊尔分离出的产 NDM 型金属β-内酰胺酶和 16S rRNA 甲基酶 ArmA 的高度多药耐药临床分离株。
Highly multidrug-resistant clinical isolates from Nepal co-producing NDM-type metallo-β-lactamases and the 16S rRNA methylase ArmA.
机构信息
Department of Microbiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
Department of Microbiology, Juntendo University Graduate School of Medicine, Tokyo, Japan.
出版信息
J Med Microbiol. 2020 Apr;69(4):572-575. doi: 10.1099/jmm.0.001160.
can harbour extended-spectrum β-lactamases and carbapenemases, resulting in increased resistance to multiple antibiotics and a high mortality rate. This study describes the emergence of highly multidrug-resistant clinical isolates of from Nepal co-producing NDM-type metallo-β-lactamases, including NDM-1 and NDM-5, and the 16S rRNA methylase ArmA. This is the first report of clinical isolates from Nepal co-producing NDM-1/-5 and ArmA. It is important to establish infection control systems and effective treatments against multidrug-resistant .
能够携带扩展谱β-内酰胺酶和碳青霉烯酶，导致对多种抗生素的耐药性增加和高死亡率。本研究描述了在尼泊尔出现的同时产 NDM 型金属β-内酰胺酶（包括 NDM-1 和 NDM-5）和 16S rRNA 甲基酶 ArmA 的高度多重耐药性临床分离株。这是尼泊尔首次报告同时产 NDM-1/-5 和 ArmA 的 临床分离株。建立针对多重耐药 的感染控制系统和有效治疗方法非常重要。
Zotero 插件