比较女性自报、专家选择和计算机选择的宫颈粘液高峰日与盲法尿黄体生成素激增，以同时识别排卵。
Comparison of woman-picked, expert-picked, and computer-picked Peak Day of cervical mucus with blinded urine luteinising hormone surge for concurrent identification of ovulation.
机构信息
Office of Cooperative Reproductive Health, Division of Public Health, Department of Family & Preventive Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.
Greater Glasgow Health Board, Glasgow, UK.
出版信息
Paediatr Perinat Epidemiol. 2020 Mar;34(2):105-113. doi: 10.1111/ppe.12642.
BACKGROUND
Previous research has demonstrated that women instructed in fertility awareness methods can identify the Peak Day of cervical mucus discharge for each menstrual cycle, and the Peak Day has high agreement with other indicators of the day of ovulation. However, previous studies enrolled experienced users of fertility awareness methods or were not fully blinded.
OBJECTIVE
To assess the agreement between cervical mucus Peak Day identified by fertile women without prior experience on assessing cervical mucus discharge with the estimated day of ovulation (1 day after urine luteinising hormone surge).
METHODS
This study is a secondary analysis of data from a randomised trial of the Creighton Model FertilityCare System (CrM), conducted 2003-2006, for women trying to conceive. Women who had no prior experience tracking cervical mucus recorded vulvar observations daily using a standardised assessment of mucus characteristics for up to seven menstrual cycles. Four approaches were used to identify the Peak Day. The referent day was defined as one day after the first identified day of luteinising hormone (LH) surge in the urine, assessed blindly. The percentage of agreement between the Peak Day and the referent day of ovulation was calculated.
RESULTS
Fifty-seven women with 187 complete cycles were included. A Peak Day was identified in 117 (63%) cycles by women, 185 (99%) cycles by experts, and 187 (100%) by computer algorithm. The woman-picked Peak Day was the same as the referent day in 25% of 117 cycles, within ±1 day in 58% of cycles, ±2 days in 84%, ±3 days in 87%, and ±4 days in 92%. The ±1 day and ± 4 days' agreement was 50% and 90% for the expert-picked and 47% and 87% for the computer-picked Peak Day, respectively.
CONCLUSIONS
Women's daily tracking of cervical mucus is a low-cost alternative for identifying the estimated day of ovulation.
背景
先前的研究表明，接受生育能力认知法培训的女性可以识别出每个月经周期宫颈粘液分泌的高峰日，并且该高峰日与其他排卵日的指标高度一致。然而，先前的研究招募的是生育能力认知法有经验的使用者，或者没有完全进行盲法。
目的
评估没有生育能力认知法经验的女性通过宫颈粘液识别出的高峰日与估计的排卵日（尿液黄体生成素激增后 1 天）的一致性。
方法
本研究是对 2003 年至 2006 年期间进行的克里顿生育保健系统（CrM）随机试验的二次分析，旨在研究试图怀孕的女性。没有追踪宫颈粘液经验的女性每天使用标准化的粘液特征评估记录外阴观察，最多记录七个月经周期。使用四种方法来识别高峰日。参考日定义为尿液中首次识别的黄体生成素（LH）激增后一天，盲法评估。计算高峰日与排卵参考日之间的一致率。
结果
共有 57 名女性完成了 187 个完整周期，其中 117 个（63%）周期由女性识别出高峰日，185 个（99%）周期由专家识别出，187 个（100%）周期由计算机算法识别出。在 117 个周期中，有 25%的周期女性选择的高峰日与参考日相同，58%的周期在±1 天内，84%的周期在±2 天内，87%的周期在±3 天内，92%的周期在±4 天内。专家选择的高峰日和计算机选择的高峰日的±1 天和±4 天一致性分别为 50%和 90%以及 47%和 87%。
结论
女性对宫颈粘液的日常追踪是识别估计排卵日的低成本替代方法。
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