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一名高嗜酸性粒细胞综合征患者发生嗜酸性粒细胞性颞动脉炎和指端缺血

Development of Eosinophilic Temporal Arteritis and Digital Ischemia in a Patient with Hypereosinophilic Syndrome.

作者信息

Ishii Kayo, Mizuuchi Takahiro, Yamamoto Yusuke, Mori Hiroaki, Tago Mayu, Kato Eri, Hayashi Haeru, Tahara Koichiro, Sawada Tetsuji

机构信息

Department of Rheumatology, Tokyo Medical University Hospital, Japan.

出版信息

Intern Med. 2020 May 15;59(10):1323-1330. doi: 10.2169/internalmedicine.3707-19. Epub 2020 Feb 26.

DOI:10.2169/internalmedicine.3707-19
PMID:32101832
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7303445/
Abstract

We describe a case of eosinophilic temporal arteritis in a 61-year-old woman with hypereosinophilic syndrome, who developed subcutaneous nodules in the temporal areas and digital cyanosis with small nodules on the sides of her fingers. Ultrasound revealed occlusion and corkscrew-like changes of the temporal and digital arteries, respectively. Temporal artery biopsy revealed eosinophilic vasculitis without giant cell formation. Angiography showed occlusion of the ulnar and digital arteries. Administration of low-dose corticosteroid improved the temporal artery swelling and digital cyanosis. More reports of similar cases are required to characterize this type of non-giant cell eosinophilic vasculitis that affects the peripheral arteries.

摘要

我们描述了一例61岁患有高嗜酸性粒细胞综合征的女性嗜酸性颞动脉炎病例，该患者颞部出现皮下结节，手指出现发绀并伴有手指侧面小结节。超声检查分别显示颞动脉和指动脉闭塞及螺旋状改变。颞动脉活检显示嗜酸性血管炎，无巨细胞形成。血管造影显示尺动脉和指动脉闭塞。给予低剂量皮质类固醇可改善颞动脉肿胀和手指发绀。需要更多类似病例报告来明确这种累及外周动脉的非巨细胞嗜酸性血管炎的特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bd/7303445/faa4fbba9e77/1349-7235-59-1323-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bd/7303445/59ae002186fc/1349-7235-59-1323-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bd/7303445/157044972c42/1349-7235-59-1323-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bd/7303445/11c9719a92a5/1349-7235-59-1323-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bd/7303445/faa4fbba9e77/1349-7235-59-1323-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bd/7303445/59ae002186fc/1349-7235-59-1323-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bd/7303445/157044972c42/1349-7235-59-1323-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bd/7303445/11c9719a92a5/1349-7235-59-1323-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1bd/7303445/faa4fbba9e77/1349-7235-59-1323-g004.jpg

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Eosinophilic disorders: evaluation of current classification and diagnostic criteria, proposal of a practical diagnostic algorithm.嗜酸性粒细胞增多性疾病：当前分类与诊断标准的评估，实用诊断算法的建议
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Intern Med. 2019 Mar 15;58(6):871-875. doi: 10.2169/internalmedicine.1167-18. Epub 2018 Nov 19.
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