Dermatology Department, Brighton General Hospital, Brighton and Sussex University Hospital NHS Trust, Brighton, United Kingdom,
Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
Dermatology. 2021;237(2):236-247. doi: 10.1159/000506045. Epub 2020 Feb 26.
Podoconiosis is a form of lymphoedema that occurs in tropical highland areas in genetically susceptible individuals who are exposed to irritant volcanic soils. The disease is preventable through consistent use of footwear and attention to foot hygiene; however, in endemic areas there is a strong barefoot tradition, and many cannot afford shoes. Patients with podoconiosis face significant physical disability, psychological comorbidity, reduced quality of life and experience frequent episodes of systemic illness due to acute dermatolymphangioadenitis. This review provides an overview of this important and neglected tropical skin disease and summarizes the latest research findings.
疣状足是一种淋巴水肿,发生在遗传易感个体暴露于刺激性火山土壤的热带高地地区。这种疾病可以通过持续穿鞋和注意脚部卫生来预防;然而,在流行地区,赤脚传统非常强烈,许多人买不起鞋子。疣状足患者面临严重的身体残疾、心理共病、生活质量下降,并因急性皮肤淋巴管炎而频繁发作全身性疾病。本文综述了这种重要而被忽视的热带皮肤疾病,并总结了最新的研究发现。