大网膜：卵巢癌转移前的生态位。
The omentum, a niche for premetastatic ovarian cancer.
机构信息
Department of Microbiology and Immunology, Weill Cornell Medicine, New York, NY.
出版信息
J Exp Med. 2020 Apr 6;217(4). doi: 10.1084/jem.20192312.
Abstract
The work by Etzerodt et al. in this issue of JEM (https://doi.org/10.1084/jem.20191869) identifies a distinct omentum-resident macrophage population of embryonic origin and demonstrates that these cells provide a niche for ovarian cancer metastasis and cancer stemness. This research opens up for many questions and therapeutic prospects.
摘要
本文由 Etzerodt 等人撰写，发表在本期《细胞— 杂志》（https://doi.org/10.1084/jem.20191869），文中鉴定了一种源自胚胎的独特的网膜驻留巨噬细胞群，并证实这些细胞为卵巢癌转移和癌症干性提供了一个龛位。这一研究提出了许多问题和治疗前景。
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