Roddy Gavin W, Zhao Bingying, Wang Feng, Fang Chengbo, Khanna Sunil S, Bajric Jasmina, Khanna Cheryl L
Department of Ophthalmology, Mayo Clinic, 200 First St SW, Rochester, MN, USA.
Department of Ophthalmology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Graefes Arch Clin Exp Ophthalmol. 2020 Jul;258(7):1533-1541. doi: 10.1007/s00417-020-04630-x. Epub 2020 Feb 26.
To determine the degree and rate of ptosis in patients undergoing glaucoma and cataract surgery.
Patients undergoing cataract extraction (CE), trabeculectomy, or glaucoma drainage device (GDD) placement, or a combination, were consecutively enrolled by a sole surgeon. Eyelid measurements, including margin reflex distance 1 (MRD1) and levator function, were obtained preoperatively and at 1 and 3 months postoperatively. Primary outcome measures were the change in MRD1 pre- vs postoperatively; percentage of patients with ptosis (defined as MRD1 < 2 mm pre- vs postoperatively). Secondary measures were the absolute change in MRD1 between groups, decrease in MRD1 of ≥ 2 mm, and change in levator function.
In total, 104 eyes of 73 patients underwent CE, trabeculectomy, or GDD placement and completed at least 1-month follow-up; 93 eyes of 65 patients completed 3-month follow-up. MRD1 decreased significantly in trabeculectomy and GDD groups at 1 and 3 months postoperatively, while it did not change in the CE group. The GDD group had a significant increase in percentage of patients with ptosis at 3 months postoperatively.
Patients who underwent glaucoma surgery, especially those who underwent GDD placement, were more likely to have postoperative ptosis than patients undergoing CE alone. High ptosis rates in patients undergoing glaucoma surgery may warrant preoperative counseling and post-operative referral to oculoplastic surgeons.
确定接受青光眼和白内障手术患者的上睑下垂程度及发生率。
由一名外科医生连续纳入接受白内障摘除术(CE)、小梁切除术或青光眼引流装置(GDD)植入术或联合手术的患者。术前及术后1个月和3个月进行眼睑测量,包括边缘反射距离1(MRD1)和提上睑肌功能。主要观察指标为术前与术后MRD1的变化;上睑下垂患者的百分比(定义为术前与术后MRD1<2mm)。次要指标为组间MRD1的绝对变化、MRD1下降≥2mm以及提上睑肌功能变化。
共有73例患者的104只眼接受了CE、小梁切除术或GDD植入术并完成了至少1个月的随访;65例患者的93只眼完成了3个月的随访。小梁切除术和GDD植入术组术后1个月和3个月MRD1显著下降,而CE组未发生变化。GDD植入术组术后3个月上睑下垂患者百分比显著增加。
与单纯接受CE的患者相比,接受青光眼手术的患者,尤其是接受GDD植入术的患者,术后更易发生上睑下垂。青光眼手术患者的高上睑下垂发生率可能需要术前咨询,并在术后转诊至眼整形科医生处。