Nilforushan Naveed, Es'haghi Acieh, Jafari Samira, Abdolalizadeh Parya, Miraftabi Arezoo, Chaibakhsh Samira, Kashkouli Mohsen Bahmani
Eye Research Center, The Five Senses Institute, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Department of Ophthalmology, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Curr Ophthalmol. 2022 Jan 6;33(4):388-393. doi: 10.4103/joco.joco_120_21. eCollection 2021 Oct-Dec.
To investigate the frequency of persistent postoperative ptosis (PP) following trabeculectomy or Ahmed glaucoma valve (AGV) implantation and to analyze the associated factors.
It is a prospective observational study on glaucoma patients who underwent trabeculectomy or AGV implantation from October 2015 to June 2017 in a tertiary center. Margin reflex distance 1 and 2 (MRD1 and 2) and levator function were measured before and at least 6 months, postoperatively. Clinically significant ptosis was defined as ≥2 mm drop of MRD1.
One hundred and fourteen patients (124 eyelids) including 76 patients (87 eyelids) with trabeculectomy and 35 patients (37 eyelids) with AGV implantation were included. The mean age was 55.50 (standard deviation = 17.54) years. Most of the surgeries were performed under general anesthesia (87.9%, 109/124) between 30 and 60 min (53.2%, 66/124) by residents (39.5%, 49/124). Trabeculectomy and AGV groups did not differ in terms of pre, intra, and postoperative variables (0.1≤ ≤0.9) except duration of surgery ( = 0.01) and sex ( = 0.04). Clinically significant persistent PP was observed in 12.9% (16/124) in total, 13.7% (12/87) in the trabeculectomy group, and 10.8% (4/37) in the AGV group ( = 0.6). Male gender (ß coefficient = 2.56, 95% confidence interval (CI) = 4.76-0.36, = 0.02) and a higher preoperative MRD1 (ß coefficient = 1.24, 95% CI = 0.52-1.95, = 0.001) were the only factors affecting the frequency of clinically significant PP.
Postoperative blepharoptosis occurred in 12.9% of eyes after glaucoma procedures. Male gender and higher preoperative MRD1 were significantly associated with a higher frequency of postglaucoma surgery blepharoptosis.
探讨小梁切除术或艾哈迈德青光眼引流阀(AGV)植入术后持续性上睑下垂(PP)的发生率,并分析相关因素。
这是一项对2015年10月至2017年6月在一家三级中心接受小梁切除术或AGV植入术的青光眼患者进行的前瞻性观察研究。术前及术后至少6个月测量边缘反射距离1和2(MRD1和MRD2)以及提上睑肌功能。临床上显著的上睑下垂定义为MRD1下降≥2mm。
纳入114例患者(124只眼),其中76例患者(87只眼)行小梁切除术,35例患者(37只眼)行AGV植入术。平均年龄为55.50(标准差=17.54)岁。大多数手术在全身麻醉下进行(87.9%,109/124),手术时间在30至60分钟之间(53.2%,66/124),由住院医师完成(39.5%,49/124)。除手术时间(P=0.01)和性别(P=0.04)外,小梁切除术组和AGV组在术前、术中及术后变量方面无差异(0.1≤P≤0.9)。总共12.9%(16/124)的患者观察到临床上显著的持续性PP,小梁切除术组为13.7%(12/87),AGV组为10.8%(4/37)(P=0.6)。男性(β系数=2.56,95%置信区间(CI)=4.76-0.36,P=0.02)和术前较高的MRD1(β系数=1.24,95%CI=0.52-1.95,P=0.001)是影响临床上显著PP发生率的唯一因素。
青光眼手术后12.9%的眼发生术后上睑下垂。男性和术前较高的MRD1与青光眼手术后上睑下垂的较高发生率显著相关。