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The Association of Metabolic Syndrome and Insulin Resistance in Early-Onset Androgenetic Alopecia in Males: A Case-Control Study.男性早发性雄激素性秃发中代谢综合征与胰岛素抵抗的关联:一项病例对照研究。
Indian J Dermatol. 2019 Jan-Feb;64(1):23-27. doi: 10.4103/ijd.IJD_724_16.
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Clinical Profile of Androgenic Alopecia and Its Association with Cardiovascular Risk Factors.雄激素性脱发的临床特征及其与心血管危险因素的关联。
Indian J Dermatol. 2019 Jan-Feb;64(1):19-22. doi: 10.4103/ijd.IJD_526_16.
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Dissection of genetic variation and evidence for pleiotropy in male pattern baldness.男性型脱发的遗传变异分析及多效性证据。
Nat Commun. 2018 Dec 20;9(1):5407. doi: 10.1038/s41467-018-07862-y.
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Medical Comorbidities and the Onset of Androgenetic Alopecia: A Population-Based, Case-Control Study.医学合并症与雄激素性脱发的发病:一项基于人群的病例对照研究。
Ann Dermatol. 2018 Apr;30(2):251-252. doi: 10.5021/ad.2018.30.2.251. Epub 2018 Feb 21.
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The Association between Exercise and Androgenetic Alopecia: A Survey-Based Study.运动与雄激素性脱发之间的关联:一项基于调查的研究。
Ann Dermatol. 2017 Aug;29(4):513-516. doi: 10.5021/ad.2017.29.4.513. Epub 2017 Jun 21.
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The combination of overweight and smoking increases the severity of androgenetic alopecia.超重和吸烟的组合会加重雄性激素源性脱发的严重程度。
Int J Dermatol. 2017 Aug;56(8):862-867. doi: 10.1111/ijd.13652. Epub 2017 May 29.
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Androgenetic alopecia: a review.雄激素性脱发:综述
Endocrine. 2017 Jul;57(1):9-17. doi: 10.1007/s12020-017-1280-y. Epub 2017 Mar 28.
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Frequency, severity and related factors of androgenetic alopecia in dermatology outpatient clinic: hospital-based cross-sectional study in Turkey.皮肤科门诊雄激素性脱发的发病率、严重程度及相关因素:土耳其一项基于医院的横断面研究
An Bras Dermatol. 2017 Jan-Feb;92(1):35-40. doi: 10.1590/abd1806-4841.20175241.
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Benign prostatic hyperplasia, metabolic syndrome and androgenic alopecia: Is there a possible relationship?良性前列腺增生、代谢综合征与雄激素性脱发:是否存在潜在关联?
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Metabolic syndrome in androgenic alopecia.雄激素性脱发中的代谢综合征
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雄激素性脱发:与人体测量指标、血压及生活方式习惯的关系

Androgenetic Alopecia: Relationship to Anthropometric Indices, Blood Pressure and Life-Style Habits.

作者信息

Danesh-Shakiba Mohammad, Poorolajal Jalal, Alirezaei Pedram

机构信息

School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran.

出版信息

Clin Cosmet Investig Dermatol. 2020 Feb 5;13:137-143. doi: 10.2147/CCID.S231940. eCollection 2020.

DOI:10.2147/CCID.S231940
PMID:32104040
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7008189/
Abstract

PURPOSE

The association of androgenetic alopecia (AGA) with cardiovascular risk factors including hypertension, smoking and high body mass index (BMI) has been investigated in several studies. However, the results are discrepant. The aim of the present study was to evaluate the association of AGA with anthropometrics, blood pressure and lifestyle habits.

PATIENTS AND METHODS

In this case-control study, 256 men with AGA and 256 age-matched healthy controls were evaluated. Systolic and diastolic blood pressures, as well as anthropometric indices were measured. Data on lifestyle habits including smoking, hookah use and alcohol consumption were also collected.

RESULTS

Patients with AGA had significantly lower BMI and lower waist to hip ratio as compared to controls (p = 0.012 and p = 0.002, respectively). Other anthropometrics as well as mean systolic and diastolic blood pressures were not significantly different between the two groups. There was no significant difference between patients and controls in terms of lifestyle habits. Patients with severe AGA (Norwood-Hamilton classification type IV-VII) had significantly higher systolic and diastolic blood pressures as compared to those with mild to moderate AGA (Norwood-Hamilton classification type II, III), but the mean age of the former group was also significantly higher (p < 0.001).

CONCLUSION

In contrast to some previous studies, our findings did not show a significant association between certain cardiovascular risk factors (such as hypertension and smoking) and AGA. Although lower BMI and lower waist to hip ratio were observed in the patient group, these values were within normal limits and therefore not biologically significant.

摘要

目的

多项研究已对雄激素性脱发(AGA)与包括高血压、吸烟和高体重指数(BMI)在内的心血管危险因素之间的关联进行了调查。然而,结果并不一致。本研究的目的是评估AGA与人体测量学、血压和生活习惯之间的关联。

患者与方法

在这项病例对照研究中,对256名AGA男性患者和256名年龄匹配的健康对照者进行了评估。测量了收缩压和舒张压以及人体测量指标。还收集了包括吸烟、水烟使用和饮酒在内的生活习惯数据。

结果

与对照组相比,AGA患者的BMI显著更低,腰臀比也更低(分别为p = 0.012和p = 0.002)。两组之间的其他人体测量指标以及平均收缩压和舒张压没有显著差异。患者和对照组在生活习惯方面没有显著差异。重度AGA(诺伍德 - 汉密尔顿分类IV - VII型)患者的收缩压和舒张压显著高于轻度至中度AGA(诺伍德 - 汉密尔顿分类II、III型)患者,但前一组的平均年龄也显著更高(p < 0.001)。

结论

与之前的一些研究不同,我们的研究结果并未显示某些心血管危险因素(如高血压和吸烟)与AGA之间存在显著关联。尽管在患者组中观察到较低的BMI和较低的腰臀比,但这些值在正常范围内,因此在生物学上不具有显著意义。