Salimonu L S, Ladipo O A, Adeniran S O, Osukoya B O
Int J Gynaecol Obstet. 1978;16(2):119-23. doi: 10.1002/j.1879-3479.1978.tb00410.x.
Immunoglobulin (Ig) levels (IgG, IgA, IgM and IgD) were measured in 92 paired maternal and cord sera by the modified single radial immunodiffusion method. There was a progressive increase in mean IgG levels as the gestational age increased which reached a maximum of 1771 mg/100 ml in the postmature babies. The mean IgG level of infants of 32--36 weeks' gestation was lowest (1395 mg/100 ml). The maternal IgG levels were generally higher than those of the cord sera. The mean maternal IgG level (1773 mg/100 ml) was considerably higher than the corresponding level in the cord sera of the lowest gestational age group. Such marked difference was not present in newborns who were of normal gestational ages. The mean IgA and IgM levels of the cord sera were low. There were no significant differences between the mean IgA and IgM levels of newborns in different gestational age groups, even when their mothers showed variations in mean IgA and IgM levels. There was no detectable level of IgD in the cord sera.
采用改良单向放射免疫扩散法检测了92对母婴血清中的免疫球蛋白（Ig）水平（IgG、IgA、IgM和IgD）。随着胎龄增加，平均IgG水平逐渐升高，过期产儿中最高可达1771mg/100ml。孕32 - 36周婴儿的平均IgG水平最低（1395mg/100ml）。母亲的IgG水平通常高于脐带血清中的水平。母亲的平均IgG水平（1773mg/100ml）显著高于胎龄最小组脐带血清中的相应水平。正常胎龄的新生儿中不存在如此明显的差异。脐带血清中IgA和IgM的平均水平较低。不同胎龄组新生儿的平均IgA和IgM水平之间无显著差异，即使其母亲的平均IgA和IgM水平存在差异。脐带血清中未检测到IgD水平。
