Konyagoz Eye Hospital, Konya, Turkey.
J Ocul Pharmacol Ther. 2020 May;36(4):234-237. doi: 10.1089/jop.2019.0085. Epub 2020 Feb 27.
To evaluate the reduction of conjunctival and episcleral hyperemia and bleeding in pterygium surgery following the use of topical brimonidine preoperatively. In this study, 45 patients who had undergone pterygium surgery under topical anesthesia were enrolled. Brominidine tartrate 0.15% eye drops were applied topically to 25 eyes of 25 patients at the sixth and third minutes preoperatively, and no drops were applied to 20 eyes of 20 patients for vasoconstriction. Preoperative and postoperative photographs and video images were taken. Vasoconstriction effects of topical brimonidine tartrate on surface vessels were observed. The surface area of blood vessels was reduced 60% within 5 min; this effect was observed with the help of Photoshop and ImageJ programs and it lasted for ∼20 min. The surgery lasts for 7 min, on average, so the conjunctival whitening formed by brimonidine tartrate provides a safe and comfortable operative area throughout the surgery. We recommend applying brimonidine tartrate before pterygium surgery due to its conjunctival whitening effect to provide a safe and comfortable operative area throughout the surgery.
评估术前局部应用溴莫尼定对翼状胬肉手术后结膜和巩膜充血及出血减少的作用。本研究纳入了 45 例在局部麻醉下接受翼状胬肉手术的患者。25 例患者的 25 只眼术前 6 分钟和 3 分钟时滴用溴莫尼定滴眼液 0.15%,20 例患者的 20 只眼不滴药进行血管收缩。拍摄术前和术后的照片和视频图像。观察局部溴莫尼定对表面血管的血管收缩作用。在 Photoshop 和 ImageJ 程序的帮助下,血管表面积在 5 分钟内减少了 60%,这种作用持续了约 20 分钟。手术平均持续 7 分钟,因此,溴莫尼定引起的结膜苍白为整个手术提供了安全舒适的手术区域。我们建议在翼状胬肉手术前应用溴莫尼定,因为其结膜苍白作用可为整个手术提供安全舒适的手术区域。