Dworák O, Tschubel K, Zhou H, Meybehm M
Pathologisches Institut der Universität Bonn.
Klin Wochenschr. 1988 Jul 1;66(13):591-5. doi: 10.1007/BF01720834.
A rare case of a 43-year-old man with polyneuropathy, monoclonal gammopathy, myeloma and Castleman's disease of plasma cell type was diagnosed. Immunohistological examination of the lymph node with Castleman's disease showed polyclonal binding while the myeloma was monoclonal containing IgA with lambda-light chains. At the immunoelectrophoresis IgA/IgA paraprotein was demonstrated. The possible pathogenetical relationship between polyneuropathy and plasmacytoma as well as Castleman's disease will be discussed.
诊断出一例罕见病例,患者为43岁男性,患有多神经病、单克隆丙种球蛋白病、骨髓瘤和浆细胞型卡斯特曼病。对患有卡斯特曼病的淋巴结进行免疫组织学检查显示为多克隆结合,而骨髓瘤为单克隆,含有IgA和λ轻链。免疫电泳显示存在IgA/IgA副蛋白。将讨论多神经病与浆细胞瘤以及卡斯特曼病之间可能的发病机制关系。