University of Ottawa, Ottawa, ON.
Department of Traumatology and Acute Critical Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
CJEM. 2020 May;22(3):342-349. doi: 10.1017/cem.2019.499.
Acute heart failure and chronic obstructive pulmonary disease (COPD) are sometimes difficult to differentiate in the emergency department (ED). We sought to determine the clinical impact of point-of-care ultrasonography (POCUS) in ED patients with suspected acute heart failure or COPD.
We conducted a prospectively collected cohort study with health records review with frequency matching at The Ottawa Hospital between March and September 2017. We included patients aged 50 and older with shortness of breath or cough from suspected acute heart failure or COPD. Our primary outcome was ED length of stay. Secondary outcomes were time to disposition decision, time to appropriate treatment, and the incidence of adverse events. We analyzed time-to-event outcomes using Kaplan-Meier analysis and Cox regression analysis with POCUS analyzed as a time-dependent variable, and the incidence of adverse events using logistic regression analyses.
There were 81 patients evaluated with lung POCUS and 243 matched patients who were not. Lung POCUS was not significantly associated with ED length of stay and time to disposition decision; however, patients evaluated with lung POCUS received disease-specific treatment faster compared with the non-POCUS group (adjusted hazard ratio, 1.50 [95% confidence interval, 1.05-2.15], a median time difference of 31 minutes). We found no significant differences in the incidence of adverse events.
In this study, use of lung POCUS resulted in no difference in ED length of stay and time to disposition decision, but was associated with faster administration of disease-specific treatments for elderly patients with suspected acute heart failure or COPD.
急性心力衰竭和慢性阻塞性肺疾病(COPD)在急诊科有时难以区分。我们旨在确定床边超声(POCUS)在急诊科疑似急性心力衰竭或 COPD 患者中的临床应用价值。
我们进行了一项前瞻性队列研究,回顾了 2017 年 3 月至 9 月在渥太华医院的健康记录,并进行了频率匹配。我们纳入了年龄在 50 岁及以上、因疑似急性心力衰竭或 COPD 而出现呼吸急促或咳嗽的患者。主要结局为急诊科住院时间。次要结局为处置决策时间、获得适当治疗的时间以及不良事件的发生率。我们使用 Kaplan-Meier 分析和 Cox 回归分析对时间依赖变量进行分析,使用逻辑回归分析对不良事件的发生率进行分析。
有 81 例患者接受了肺部 POCUS 评估,有 243 例匹配患者未接受 POCUS 评估。肺部 POCUS 与急诊科住院时间和处置决策时间无显著相关性;然而,接受肺部 POCUS 评估的患者比未接受 POCUS 评估的患者更快地接受了疾病特异性治疗(调整后的危险比,1.50[95%置信区间,1.05-2.15],中位数时间差为 31 分钟)。我们未发现不良事件发生率的显著差异。
在这项研究中,肺部 POCUS 的使用并未导致急诊科住院时间和处置决策时间的差异,但与疑似急性心力衰竭或 COPD 的老年患者更快地接受疾病特异性治疗相关。