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前列腺动脉栓塞术治疗良性前列腺增生症患者排尿及储尿症状的四年影响

Four-Year Impact of Voiding and Storage Symptoms in Patients with Benign Prostatic Hyperplasia Treated with Prostatic Artery Embolization.

作者信息

Lin Yen-Ting, Pereira Héléna, Pellerin Olivier, Déan Carole, Thiounn Nicolas, Sapoval Marc

机构信息

Department of Interventional Radiology, Assistance publique Hopitaux de Paris, Hôpital Européen Georges-Pompidou, Paris, France; Department of Radiology, Taichung Veterans General Hospital, 1650 Taiwan Boulevard Sect., 40705 Taichung, Taiwan.

Department of Interventional Radiology, Assistance publique Hopitaux de Paris, Hôpital Européen Georges-Pompidou, Paris, France.

出版信息

J Vasc Interv Radiol. 2020 Sep;31(9):1460-1466. doi: 10.1016/j.jvir.2019.08.034. Epub 2020 Feb 24.

DOI:10.1016/j.jvir.2019.08.034
PMID:32107124
Abstract

PURPOSE

To study the subscore improvement in International Prostate Symptom Scores (IPSS) after prostatic artery embolization (PAE).

MATERIALS AND METHODS

A single-center retrospective study was carried out with follow-up from December 2013 to July 2019 in 37 consecutive patients (66.0 ± 8.8 years old) who underwent PAE, comparing resultant scores before and after PAE. IPSS were divided into storage (IPSS-s) subscores and voiding (IPSS-v) subscores. The changes between IPSS-s and IPSS-v at 1, 3, 6, and 12 months' follow-up as well as the last follow-up were compared with baseline scores. The changes in percentages of IPSS-s and IPSS-v and the changes in average IPSS-s-to-total IPSS ratios (IPSS-s/IPSS-t) and IPSS-v-to-IPSS-t ratios (IPSS-v/IPSS-t) were also analyzed.

RESULTS

In the study population, consisting of 37 patients, IPSS-t significantly decreased from 16.5 ± 7.2 at baseline to 8.3 ± 5.7 at the last follow-up (4 years later) (P < .0001). Additionally, the changes in IPSS-v symptoms were greater than the changes in IPSS-s symptoms at 1, 3, 6, and 12 months' follow-up, reaching a statistical significance at 6 months with a decrease of 72.9% ± 42.4% for IPSS-v and a decrease of 50.1% ± 52.2% for IPSS-s (P = .009).

CONCLUSIONS

PAE can successfully reduce both IPSS-s and IPSS-v with predominant IPSS-v reduction. The improvements in both subscores were sustained for up to 4 years of follow-up.

摘要

目的

研究前列腺动脉栓塞术(PAE)后国际前列腺症状评分(IPSS)各子评分的改善情况。

材料与方法

进行一项单中心回顾性研究,对2013年12月至2019年7月期间连续37例接受PAE的患者(年龄66.0±8.8岁)进行随访,比较PAE前后的评分结果。IPSS分为储尿(IPSS-s)子评分和排尿(IPSS-v)子评分。将1、3、6和12个月随访以及末次随访时IPSS-s和IPSS-v的变化与基线评分进行比较。还分析了IPSS-s和IPSS-v百分比的变化以及IPSS-s与总IPSS比值(IPSS-s/IPSS-t)和IPSS-v与IPSS-t比值(IPSS-v/IPSS-t)的变化。

结果

在由37例患者组成的研究人群中,IPSS-t从基线时的16.5±7.2显著降至末次随访时(4年后)的8.3±5.7(P<.0001)。此外,在1、3、6和12个月随访时,IPSS-v症状的变化大于IPSS-s症状的变化,在6个月时达到统计学显著性,IPSS-v下降72.9%±42.4%,IPSS-s下降50.1%±52.2%(P=.009)。

结论

PAE可成功降低IPSS-s和IPSS-v,其中IPSS-v降低更为显著。两个子评分的改善在长达4年的随访中持续存在。

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