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经钬激光前列腺剜除术后患者的短期术后恢复:下尿路症状对生活质量影响的评估。

Short-term postoperative recovery for patients after Thulium Laser Vapoenucleation of Prostate: evaluation of the impact of lower urinary tract symptoms on quality of life.

机构信息

Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Wujin Road No.85, Hongkou District, Shanghai, China.

Department of Pathology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

出版信息

World J Urol. 2024 Oct 23;42(1):587. doi: 10.1007/s00345-024-05293-7.

Abstract

PURPOSE

We evaluated short-term postoperative recovery in patients with benign prostatic hyperplasia (BPH), especially focusing on symptoms reduction and life quality enhancement.

METHODS

We prospectively enrolled 160 BPH patients who underwent surgery and were followed up regularly for 12 weeks, collecting the International Prostate Symptom Score (IPSS), Quality of Life (QoL), and Qmax. Regression analysis and mixed effect models were used to evaluate the tendency of symptoms on recovery from the perspective of quality of life.

RESULTS

At 12 weeks, all patients recovered well with conspicuous change in IPSS, QoL and Qmax, that were 4.80 ± 4.59, 1.34 ± 1.14,20.02 ± 8.61 mL/s respectively. Voiding symptoms were significantly reduced by 79.4% at 2 weeks, whereas storage symptoms recovered slowly until 12 weeks with residual lower urinary tract symptoms (LUTS), predominantly urinary frequency and nocturia. Improvements in incomplete emptying urination and urinary frequency were significantly associated with QoL.

CONCLUSIONS

With regards to the comprehensive full-cycle treatment of LUTS patients, in addition to the objective results, more attention should also be focused on the change in following symptoms, that is, incomplete emptying urination, urine frequency and urination difficulty, which play key roles in the enhancement of patients' quality of life.

摘要

目的

我们评估了良性前列腺增生(BPH)患者的短期术后恢复情况,特别是关注症状缓解和生活质量的提高。

方法

我们前瞻性地招募了 160 名接受手术治疗的 BPH 患者,并定期随访 12 周,收集国际前列腺症状评分(IPSS)、生活质量(QoL)和最大尿流率(Qmax)。回归分析和混合效应模型用于从生活质量的角度评估症状恢复的趋势。

结果

12 周时,所有患者均恢复良好,IPSS、QoL 和 Qmax 显著改善,分别为 4.80±4.59、1.34±1.14 和 20.02±8.61ml/s。排尿症状在 2 周时显著减轻了 79.4%,而储存症状恢复缓慢,直到 12 周仍有残余下尿路症状(LUTS),主要是尿频和夜尿。排尿不尽和尿频的改善与 QoL 显著相关。

结论

在 LUTS 患者的综合全周期治疗中,除了客观结果外,还应更加关注未完全排空、尿频和排尿困难等症状的变化,这些症状对患者生活质量的提高起着关键作用。

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