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仿生组装在磷脂双层中:有效调节静电和疏水相互作用,用于质膜特异性探针。

Bio-inspired assembly in a phospholipid bilayer: effective regulation of electrostatic and hydrophobic interactions for plasma membrane specific probes.

机构信息

Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, 610064, China.

出版信息

Chem Commun (Camb). 2020 Mar 26;56(25):3661-3664. doi: 10.1039/d0cc00679c.

Abstract

Inspired by the natural properties of the phospholipid bilayer (PB), three probes that could assemble with phospholipid bilayer through hydrophobic and electrostatic interactions are reported for rapid and accurate specific imaging of plasma membrane in 2D and 3D cell models. What's more, we have captured the picture of probe assembly with the phospholipid bilayer in cells for the first time.

摘要

受磷脂双层(PB)自然特性的启发,本文报道了三种通过疏水相互作用和静电相互作用与磷脂双层组装的探针,可用于快速、准确地对 2D 和 3D 细胞模型中的质膜进行特异性成像。更重要的是,我们首次在细胞中捕捉到了探针与磷脂双层组装的图像。

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