General and Pancreatic Surgery Unit, Pancreas Institute, University of Verona, Verona, Italy.
Clinical Psychology, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Psychooncology. 2020 Jun;29(6):1004-1011. doi: 10.1002/pon.5370. Epub 2020 Mar 10.
Literature shows that emotional status can influence participation in screening/surveillance programs, and that screening/surveillance programs may alter the psychological well-being of subjects examined. This study aims to assess if participating in a surveillance program for pancreatic cancer early detection is associated with abnormal levels of psychological distress in high-risk individuals (HRIs), compared to the general population.
Fifty-four HRIs participating in a magnetic resonance cholangiopancreatography (MRCP)-based surveillance program completed several psychological assessment questionnaires, investigating global functioning, self-efficacy, perceived stress, coping abilities, and social support. The questionnaires were administered by a clinical psychologist after the MRCP but before the subjects were informed about the results of the scans. The HRIs were subjects with strong familiarity of pancreatic cancer and/or carriers of known genetic mutations related to cancer susceptibility. The psychological assessment was made at the time of the first examination.
The population was characterized by an overall good psychological status. Scoring of our sample was comparable to the general population norms. The HRIs showed decent global functioning, high self-efficacy levels, low perceived stress in the last month prior to examination, efficient emotion-focused coping strategies, and an adequate social support system. The younger subjects' subpopulation only revealed higher levels of stress.
From a psychological point of view, an MRCP-based pancreatic cancer annual surveillance seemed not to influence the HRIs' psychological well-being, unless in young people. Further studies are needed to better establish if there are any changes in distress levels over time and how emotional status influences participation in surveillance programs.
文献表明，情绪状态会影响参与筛查/监测计划的意愿，而筛查/监测计划可能会改变接受检查者的心理健康状况。本研究旨在评估与一般人群相比，参与胰腺癌早期检测的监测计划是否与高危个体（HRIs）的心理困扰异常水平相关。
54 名参与基于磁共振胰胆管成像（MRCP）的监测计划的 HRIs 完成了多项心理评估问卷，调查了整体功能、自我效能、感知压力、应对能力和社会支持。问卷由临床心理学家在 MRCP 检查后但在告知受试者扫描结果之前进行管理。HRIs 是对胰腺癌有强烈熟悉度的受试者，或携带与癌症易感性相关的已知基因突变的携带者。心理评估是在第一次检查时进行的。
该人群的心理状态总体良好。我们的样本评分与一般人群的正常值相当。HRIs 表现出良好的整体功能、高水平的自我效能、检查前一个月的低感知压力、有效的情绪焦点应对策略和充足的社会支持系统。年轻受试者的亚群仅显示出更高的压力水平。
从心理学角度来看，基于 MRCP 的胰腺癌年度监测似乎不会影响 HRIs 的心理健康，除非是年轻人。需要进一步的研究来更好地确定是否随着时间的推移，困扰水平是否发生变化，以及情绪状态如何影响参与监测计划的意愿。
