Vesterberg Anna, Asplund Ebba, Marras Giulia, Vujasinovic Miroslav, Haddad Ringborg Cecilia, Wengström Yvonne, Löhr Matthias
Division of Surgery and Oncology, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, Stockholm, Sweden.
Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.
BMJ Open. 2025 Apr 30;15(4):e097814. doi: 10.1136/bmjopen-2024-097814.
Pancreatic cancer, an aggressive cancer that presents with few or unspecific symptoms, has a poor prognosis. Thus, diagnosis at an early stage is vital for survival and a chance for curative treatment. Therefore, surveillance programmes for high-risk individuals are of the utmost importance. However, data on the psychological burden among participants in these programmes are limited.
This study aimed to investigate the psychological burden for participants in a pancreatic cancer surveillance programme and explore whether the psychological burden was related to the individual's risk level for pancreatic cancer.
This single-centre cross-sectional study investigated cancer worry, anxiety, coping and perceived physical and mental health using a digital questionnaire, including the following instruments: Cancer Worry Scale (CWS), State-Trait Anxiety Inventory (STAI), 13-Item Sense of Coherence and 12-Item Short-Form Survey. The invited participants (n=413) were healthy individuals with an increased risk of pancreatic cancer enrolled in a pancreatic cancer surveillance programme.
The results indicated high cancer worry among respondents (n=78) with high scores on CWS (mean, 16.45). The majority (69.3%) had scores indicating high cancer worry (14). Anxiety was not equally high among respondents (mean STAI-T, 35.13; STAI-S, 35.9). Female sex and younger age were significantly correlated with higher cancer worry and anxiety (p < 0.001). Outcomes in coping and perceived health were similar to those of the normal population.
Cancer worry is particularly high among participants. No correlation was found between the risk level and psychological burden.
胰腺癌是一种侵袭性癌症，症状较少或不具特异性，预后较差。因此，早期诊断对于生存及获得治愈性治疗的机会至关重要。所以，针对高危个体的监测项目极为重要。然而，关于这些项目参与者心理负担的数据有限。
本研究旨在调查胰腺癌监测项目参与者的心理负担，并探讨心理负担是否与个体患胰腺癌的风险水平相关。
这项单中心横断面研究使用数字问卷调查了癌症担忧、焦虑、应对方式以及感知到的身心健康状况，问卷包括以下工具：癌症担忧量表（CWS）、状态-特质焦虑量表（STAI）、13项连贯感量表和12项简短调查问卷。受邀参与者（n = 413）为纳入胰腺癌监测项目的胰腺癌风险增加的健康个体。
结果表明，癌症担忧量表得分较高（平均16.45分）的受访者（n = 78）存在较高的癌症担忧。大多数（69.3%）的得分表明存在较高的癌症担忧（14分）。受访者的焦虑程度并不相同（状态焦虑量表平均得分35.13分；特质焦虑量表平均得分35.9分）。女性和较年轻的年龄与较高的癌症担忧和焦虑显著相关（p < 0.001）。应对方式和感知健康方面的结果与正常人群相似。
参与者的癌症担忧尤为严重。未发现风险水平与心理负担之间存在相关性。
