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在肯尼亚现实世界的暴露前预防实施项目中,年轻女性中检测到替诺福韦二磷酸的频率和预测因素。

Frequency and Predictors of Tenofovir-diphosphate Detection Among Young Kenyan Women in a Real-world Pre-exposure Prophylaxis Implementation Program.

机构信息

Department of Global Health, University of Washington, Seattle, Washington, USA.

Department of Biobehavioral Nursing and Health Informatics, University of Washington, Seattle, Washington, USA.

出版信息

Clin Infect Dis. 2020 Dec 3;71(9):e509-e512. doi: 10.1093/cid/ciaa181.

Abstract

In a pre-exposure prophylaxis program for Kenyan women, we detected tenofovir-diphosphate in 61% (125/201) of randomly selected dried blood spots collected at the first follow-up visit. Tenofovir-diphosphate was detected more frequently among women who had partners living with human immunodeficiency virus, who were not pregnant, and who were ≥24 years.

摘要

在肯尼亚妇女的暴露前预防计划中,我们在第一次随访时随机采集的 201 份干燥血斑样本中,检测到 61%(125/201)含有替诺福韦二磷酸。在与携带人类免疫缺陷病毒的伴侣生活、未怀孕且年龄≥24 岁的女性中,更频繁地检测到替诺福韦二磷酸。

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