Gabnai-Nagy Erika, Bugán Antal, Bodnár Béla, Papp Gábor, Nagy Beáta Erika
Institute of Behavioural Sciences, Faculty of Public Health, University of Debrecen, Debrecen, Hungary.
Assisted Reproduction Center, Clinical Centre, University of Debrecen, Debrecen, Hungary.
Geburtshilfe Frauenheilkd. 2020 Feb;80(2):200-210. doi: 10.1055/a-0854-5987. Epub 2020 Feb 21.
Infertility and its treatment are associated with considerable psychological distress for infertile couples. The aim of our study was to explore to what extent positive and negative affectivity and a predisposition to depression and anxiety appear in infertile couples during in vitro fertilization (IVF) treatment. We also aimed to explore how the emotional state of couples changed during IVF in relation to treatment outcomes. In our longitudinal study, 174 people (87 couples) were followed up during treatment by means of questionnaires. Their emotional state was assessed with PANAS, BDI-R, and STAI at the beginning of treatment, before embryo transfer, and before taking a pregnancy test. Couples who achieved pregnancy after treatment were included in the successful group (n = 82), while those who did not were included in the unsuccessful group (n = 92). We found more favorable emotional states in IVF couples compared to patient populations and the average population. In successful IVF couples, positive affectivity decreased, and negative affectivity increased in women until the time of embryo transfer. This was accompanied by an increase in positive affectivity in men, which remained until the time of the pregnancy test and provided emotional support to their partner. These results were confirmed by changes in the levels of depression. Our study suggests the importance of couples' emotional dynamics for having a child and an association between couples' emotional reactions during IVF cycles and treatment success.
不孕不育及其治疗会给不孕夫妇带来相当大的心理困扰。我们研究的目的是探讨在体外受精（IVF）治疗期间，不孕夫妇中积极和消极情感以及抑郁和焦虑倾向的出现程度。我们还旨在探讨在IVF治疗期间，夫妇的情绪状态如何因治疗结果而发生变化。在我们的纵向研究中，通过问卷调查对174人（87对夫妇）在治疗期间进行了随访。在治疗开始时、胚胎移植前以及进行妊娠试验前，用PANAS、BDI-R和STAI评估他们的情绪状态。治疗后成功怀孕的夫妇被纳入成功组（n = 82），而未成功怀孕的夫妇被纳入失败组（n = 92）。我们发现，与患者群体和普通人群相比，IVF夫妇的情绪状态更为良好。在成功的IVF夫妇中，女性的积极情感在胚胎移植前下降，消极情感增加。与此同时，男性的积极情感增加，这种情况一直持续到妊娠试验时，并为其伴侣提供情感支持。抑郁水平的变化证实了这些结果。我们的研究表明，夫妇的情绪动态对生育孩子的重要性，以及IVF周期中夫妇的情绪反应与治疗成功之间的关联。
