Zhang Weidong, Chen Jingfang, Wu Xiaoming, Chen Luyu, Wei Jinxing, Xue Mingqiang, Liang Qingzheng
Department of Thoracic Surgery, Henan Provincial Chest Hospital, Zhengzhou, Henan Province 450003, People's Republic of China.
Diabetes Metab Syndr Obes. 2020 Feb 17;13:405-412. doi: 10.2147/DMSO.S230799. eCollection 2020.
To analyse the clinical features of pneumomediastinum associated with DKA (diabetic ketoacidosis) to improve clinicians' understanding of the disease.
A total of 78 patients with pneumomediastinum associated with DKA were identified in the literature search, and one patient treated in our hospital was included. The clinical features of the 79 patients were retrospectively analysed, and the pathogenesis, clinical symptoms, diagnostic methods, treatment strategies and prognoses were explored.
All cases were confirmed by chest CT (computed tomography), and Kussmaul respiration, severe vomiting, chest pain were common symptoms. The main treatment principle was to correct acidosis and treat the primary disease. The majority of patients recovered within 1-2 weeks, and only 2 patients died.
Pneumomediastinum associated with DKA is a rare disease, and it has a benign course when an early diagnosis is made and aetiological treatment is administered.
分析与糖尿病酮症酸中毒（DKA）相关的纵隔气肿的临床特征，以提高临床医生对该疾病的认识。
通过文献检索共纳入78例与DKA相关的纵隔气肿患者，并纳入我院治疗的1例患者。对这79例患者的临床特征进行回顾性分析，探讨其发病机制、临床症状、诊断方法、治疗策略及预后。
所有病例均经胸部CT（计算机断层扫描）确诊，库斯莫尔呼吸、严重呕吐、胸痛为常见症状。主要治疗原则是纠正酸中毒并治疗原发病。大多数患者在1 - 2周内康复，仅2例死亡。
与DKA相关的纵隔气肿是一种罕见疾病，早期诊断并进行病因治疗时病程呈良性。
