Rosenov Alexander, Schindewolf Marc, Baumgartner Iris, Saely Christoph
Division of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Department of Medicine I, Academic Teaching Hospital Feldkirch, Feldkirch, Austria.
Clin Med Insights Case Rep. 2020 Feb 17;13:1179547620906863. doi: 10.1177/1179547620906863. eCollection 2020.
Angiomyolipomas are rare benign tumors of the kidneys, with a risk of spontaneous hemorrhage including severe retroperitoneal bleedings. In this study, we report clinical outcomes of 5 patients who underwent 8 embolization sessions using 96% ethanol, as there is scarce data using this embolic agent for this indication. The primary angiographic success could be achieved in all but 1 lesion, which was not accessible due to vasospasm of the supplying vessel. Therapeutic success could be demonstrated in all treated cases for which follow-up imaging was available (n = 3). In 1 complex patient, a mildly reduced renal function, as well as a new onset of arterial hypertension was detected after treatment. Nontarget embolization of vital kidney tissue was demonstrated in another patient; it remained asymptomatic. Embolization therapy using 96% ethanol is an optional method to treat renal angiomyolipomas.
血管平滑肌脂肪瘤是一种罕见的肾脏良性肿瘤,有自发出血的风险,包括严重的腹膜后出血。在本研究中,我们报告了5例患者接受8次使用96%乙醇栓塞治疗的临床结果,因为针对该适应症使用这种栓塞剂的数据很少。除1个病灶外,所有病灶均取得了初次血管造影成功,该病灶因供血血管痉挛无法到达。在所有有随访影像学资料的治疗病例(n = 3)中均显示治疗成功。在1例复杂患者中,治疗后检测到肾功能轻度下降以及新发动脉高血压。在另一例患者中发现了重要肾组织的非靶栓塞;该患者无症状。使用96%乙醇进行栓塞治疗是治疗肾血管平滑肌脂肪瘤的一种可选方法。