Sekiguchi Ivan, Takeda Naoki, Ishida Naoki
Department of Orthopedic Surgery, Hokuto Medical Corporation Hokuto Hospital, Obihiro, Japan.
Department of Rehabilitation, Sapporo Orthopedic Cardiovascular Hospital, Sapporo, Japan.
Case Rep Oncol. 2020 Jan 20;13(1):12-16. doi: 10.1159/000504931. eCollection 2020 Jan-Apr.
Malignant fibrous histiocytoma (MFH) of the spine is rare, with only a few dozen cases reported in the literature. A 60-year-old male was referred to us with symptoms of thoracic myelopathy. A solid tumor in the Th8 right costovertebral junction invading the spinal canal and compressing the spinal cord, and multiple bony metastases were discovered. Biopsy confirmed MFH. The thoracic spine tumor showed good response to irradiation followed by embolization and partial resection. The patient was followed until his death 22 months later. A good quality of life was sustained for more than 18 months. Despite a poor prognosis and an aggressive course of MFH of the spine, a good quality of life could be sustained for more than a year with palliative interventions.
脊柱恶性纤维组织细胞瘤（MFH）较为罕见，文献中仅报道过几十例。一名60岁男性因胸椎脊髓病症状转诊至我院。发现其胸8右侧肋椎关节处有一实性肿瘤，侵犯椎管并压迫脊髓，同时伴有多处骨转移。活检确诊为MFH。胸椎肿瘤经放疗、栓塞及部分切除后显示出良好反应。对该患者进行随访直至其22个月后死亡。其生活质量在18个月以上保持良好。尽管脊柱MFH预后不良且病程进展迅速，但通过姑息性干预仍可使生活质量维持一年以上。
