Wang Gang, Ferguson David, Ionescu Diana N, Hoang Lien, Barrett Sarah, van Niekerk Dirk, Rose James Neil, Kollmannsberger Christian
Department of Pathology, BC Cancer Vancouver Centre, Vancouver, British Columbia, Canada.
University of British Columbia, Vancouver, British Columbia, Canada.
Case Rep Oncol. 2020 Jan 20;13(1):17-22. doi: 10.1159/000504936. eCollection 2020 Jan-Apr.
There have been 4 reported cases of squamous cell carcinoma (SCC) of the neovagina in transgender women. In this report, we present another case of neovaginal SCC in a transgender woman, which was HPV-related, with lung metastasis as the initial presentation, and which was also complicated by her previous history of metastatic renal cell carcinoma. This unique case highlights the diagnostic challenges in these unusual scenarios. Through this report, we hope to address the benefits of multidisciplinary tumor board rounds, provision of detailed clinical information, and familiarization of the transgender anatomy within the pelvis in this group of patients. We also propose that transgender women undergo a continuous annual follow-up after postoperative follow-up is completed.
据报道，变性女性新阴道鳞状细胞癌（SCC）已有4例。在本报告中，我们介绍了另一例变性女性新阴道SCC病例，该病例与HPV相关，以肺转移为首发表现，且患者既往有转移性肾细胞癌病史，使病情更为复杂。这一独特病例凸显了这些特殊情况下的诊断挑战。通过本报告，我们希望探讨多学科肿瘤病例讨论的益处、提供详细的临床信息以及让该组患者熟悉盆腔内变性后的解剖结构。我们还建议变性女性在术后随访完成后每年持续接受随访。
