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撒哈拉以南非洲国家一家肾脏病科收治的金矿工人肾衰竭的临床、辅助检查及病情演变特征

Clinical, Paraclinical, and Evolutionary Profiles of Kidney Failure in Gold Miners Hospitalized in a Nephrological Service in a Sub-Saharan African Country.

作者信息

Coulibaly Gérard, Sanou Gaoussou, Sanon Moumouni, Lengani Aïda H Y, Bonzi Juste Y, Semde Aoua

机构信息

Centre Hospitalier Universitaire Yalgado OUEDRAOGO, Service de Néphrologie et Hémodialyse, 03 BP 7022, Ouagadougou, Burkina Faso.

Centre Hospitalier Universitaire Sourô SANOU, Service de Néphrologie et Dialyse, Bobo-Dioulasso, Burkina Faso.

出版信息

Int J Nephrol. 2020 Feb 14;2020:4282969. doi: 10.1155/2020/4282969. eCollection 2020.

Abstract

UNLABELLED

. The purpose of this preliminary study is to describe the clinical, paraclinical, and evolutionary profiles of gold miner patients with kidney failure hospitalized in the nephrology and haemodialysis service in the Yalgado Ouédraogo University Hospital of Ouagadougou (CHU-YO). . This was a longitudinal and descriptive study with a retrospective collection of data for the period from February 1, 2013, to March 31, 2018. Included were all gold miner patients who stayed and worked at an artisanal gold mining site for at least three months and who were diagnosed with acute or chronic kidney failure during hospitalization in the nephrology service. We collected sociodemographic, clinical, and paraclinical variables at admission and then three months later.

RESULTS

We included 50 patients; all were male and the average age was 29.4 ± 7.7 years. All patients were exposed to mercury and/or cyanide for an average of 4.5 ± 2.8 years. The average consultation/referral time for patients at the CHU-YO was 25.4 ± 14.9 days. The average of creatininemia was 2338.0 ± 791.4 mol/L. Kidney failure was acute in five cases (10%) and chronic in the remaining 45 cases or 90%. Extrarenal purification was indicated in 43 cases (86%). It was not performed in nine of the 43 cases due to lack of financial resources for patients (six cases) or death prior to the onset of haemodialysis (three cases). Thirty-two of the 50 patients in the study (64% of cases) died.

CONCLUSION

Chronic kidney failure in gold miners appears to be common and late-managed. A prospective study of kidney disease and its causes at gold mining sites and surrounding areas will assess the extent of the problem in the country and better clarify the prevention of these diseases in our country.

摘要

未标注

本初步研究的目的是描述在瓦加杜古亚尔加杜·韦德拉奥果大学医院(CHU-YO)肾病和血液透析科住院的肾衰竭金矿工人的临床、辅助检查及病情演变情况。这是一项纵向描述性研究,回顾性收集了2013年2月1日至2018年3月31日期间的数据。纳入的患者为所有在手工金矿工作至少三个月且在肾病科住院期间被诊断为急性或慢性肾衰竭的金矿工人。我们在入院时及三个月后收集了社会人口统计学、临床和辅助检查变量。

结果

我们纳入了50例患者;均为男性,平均年龄为29.4±7.7岁。所有患者平均接触汞和/或氰化物4.5±2.8年。患者在CHU-YO的平均就诊/转诊时间为25.4±14.9天。血肌酐平均水平为2338.0±791.4μmol/L。5例(10%)为急性肾衰竭,其余45例(90%)为慢性肾衰竭。43例(86%)患者需要进行肾外净化治疗。43例中有9例因患者缺乏资金(6例)或在血液透析开始前死亡(3例)而未进行治疗。研究中的50例患者中有32例(64%)死亡。

结论

金矿工人慢性肾衰竭似乎很常见且治疗较晚。对金矿及其周边地区的肾病及其病因进行前瞻性研究将评估该国该问题的严重程度,并更好地明确我国这些疾病的预防措施。

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