核仁组成区嗜银蛋白作为一种有效的诊断工具，用于确定不同类型牙源性囊肿的增殖特性。

AgNOR as an effective diagnostic tool for determining the proliferative nature of different types of odontogenic cysts.

作者信息

Tyagi Krishan Kumar, Chandra Lokesh, Kumar Manoj, Singh Sameep, Passi Deepak, Goyal Jyoti, Gupta Utkarsh

机构信息

Department of Oral and Maxillofacial Pathology, Kathmandu Medical College, Nepal.

Department of Oral and Maxillofacial Surgery, ESIC Dental College and Hospital, Rohini, Delhi, India.

出版信息

J Family Med Prim Care. 2020 Jan 28;9(1):125-130. doi: 10.4103/jfmpc.jfmpc_617_19. eCollection 2020 Jan.

DOI:10.4103/jfmpc.jfmpc_617_19

PMID:32110577

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7014846/

Abstract

OBJECTIVE

To determine the proliferative nature of different types of odontogenic cysts using silver-stained nucleolar organizer region (AgNOR) staining.

MATERIALS AND METHODS

Forty histopathological sections of each of odontogenic keratocyst, dentigerous, and radicular growth were taken into study. Two sections were produced using the paraffin block of separate cases, one was stained with hematoxylin and eosin and another segment was stained with silver nitrate method.

RESULTS

AgNOR staining shows black dots and other parts of nuclei show yellow-brown dots.

CONCLUSION

AgNOR, which stain for NOR-related proteins, corresponds to cell multiplication. Their amount regarding the number of AgNORs per cyst can be a good marker of the proliferative action of the cell in aggressive cystic lesion having malignant potential.

摘要