Syed Ismail Prabu Mahin, Apoorva K, Manasa N, Rama Krishna R, Bhowmick Siddhartha, Jain Shilpa
Department of Conservative Dentistry, AL Rass Dental College, Qassim University, Kingdom of Saudi Arabia.
Department of Conservative Dentistry and Endodontics, Malla Reddy Institute of Dental Sciences, Suraram, Hyderabad, Telengana, India.
J Family Med Prim Care. 2020 Jan 28;9(1):235-238. doi: 10.4103/jfmpc.jfmpc_715_19. eCollection 2020 Jan.
The present study aimed at comparing clinical, radiographical, and histological findings in chronic periapical lesions such as cysts, granuloma, and abscess.
The present study was conducted on 148 teeth having chronic inflammatory periapical lesions with or without nonsurgical endodontic treatment. Endodontic surgery was performed by single trained endodontist. After surgical endodontic treatment, biopsy sections of teeth were assessed histologically. All slides stained with hematoxylin/eosin and Gomori trichrome for light microscopy assessment.
Out of 148 teeth, 41 had chronic inflammatory lesions, 34 had inflammatory cysts, and 25 had indefinite lesions. Chronic inflammatory lesions assessed histologically found chronic apical periodontitis in 86 cases and inflammatory cysts in 62 cases. The difference was significant ( < 0.05). Out of 86 cases of chronic apical periodontitis confirmed clinical radiographically, 64% found positive, whereas 36% were not histologically. Out of 62 cases of inflammatory cysts confirmed clinically and radiographically, 78% found positive while 36% were not histologically. Out of 25 indefinite lesions, 56% found chronic inflammatory lesions while 44% found inflammatory cyst.
There was significant disagreement in clinical radiographic as well as histological diagnosis.
本研究旨在比较慢性根尖周病变（如囊肿、肉芽肿和脓肿）的临床、影像学和组织学表现。
本研究对148颗患有慢性炎症性根尖周病变的牙齿进行，这些牙齿接受或未接受非手术根管治疗。根管手术由一名经过培训的根管治疗医生进行。根管手术后，对牙齿的活检切片进行组织学评估。所有切片用苏木精/伊红和Gomori三色染色，用于光学显微镜评估。
在148颗牙齿中，41颗有慢性炎症性病变，34颗有炎性囊肿，25颗有不确定病变。组织学评估的慢性炎症性病变中，86例为慢性根尖周炎，62例为炎性囊肿。差异具有统计学意义（<0.05）。在86例经临床影像学证实的慢性根尖周炎病例中，64%组织学检查呈阳性，而36%组织学检查未呈阳性。在62例经临床和影像学证实的炎性囊肿病例中，78%组织学检查呈阳性，而36%组织学检查未呈阳性。在25例不确定病变中，56%为慢性炎症性病变而44%为炎性囊肿。
临床影像学诊断与组织学诊断存在显著差异。
