Trope M, Pettigrew J, Petras J, Barnett F, Tronstad L
Endod Dent Traumatol. 1989 Apr;5(2):69-72. doi: 10.1111/j.1600-9657.1989.tb00339.x.
The purpose of this investigation was to study periapical lesions by means of computerized tomography to ascertain if this noninvasive method could be of value in distinguishing between radicular cysts and granulomas. Periapical radiographs were taken of the teeth of 60 human cadavers. Periapical radiolucencies were seen in conjunction with 33 teeth. Based on the periapical radiographs, an oral radiologist (J.P.) attempted to select 4 granulomas and 4 cysts from the 33 radiolucencies. Computerized tomography was performed on the root tips and the periapical lesions of these 8 teeth. The roots and periapical lesions were then surgically removed and prepared histologically for microscopic examination. In the tomographs, 7 of the periapical lesions had a cloudy appearance with a density similar to each other and to the surrounding soft tissue. In the eighth lesion a homogeneous dark area with a distinctly lower density could be distinguished from surrounding cloudy areas. Histologically, the dark area was shown to be an epithelialized cyst cavity. The other 7 lesions were granulomas. Thus, a cyst could be differentiated from periapical granulomas by computerized tomography because of a marked difference in density between the content of the cyst cavity and granulomatous tissue.
本研究的目的是通过计算机断层扫描研究根尖周病变，以确定这种非侵入性方法在区分根囊肿和肉芽肿方面是否有价值。对60具人类尸体的牙齿进行了根尖片拍摄。在33颗牙齿上发现了根尖周透射区。基于根尖片，一位口腔放射科医生（J.P.）试图从这33个透射区中挑选出4个肉芽肿和4个囊肿。对这8颗牙齿的根尖和根尖周病变进行了计算机断层扫描。然后通过手术切除牙根和根尖周病变，并进行组织学制备以进行显微镜检查。在断层扫描中，7个根尖周病变呈现出云雾状外观，其密度彼此相似且与周围软组织相似。在第八个病变中，可以从周围的云雾状区域区分出一个密度明显较低的均匀暗区。组织学检查显示，该暗区为上皮化的囊肿腔。其他7个病变为肉芽肿。因此，由于囊肿腔内容物与肉芽肿组织之间的密度存在明显差异，通过计算机断层扫描可以将囊肿与根尖周肉芽肿区分开来。
