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甲状腺功能亢进患者发热的一个不常见原因。

An uncommon cause of fever in a patient with hyperthyroidism.

作者信息

Gautam Krishna P, Lijesh Kanakkankotil U, Jude John, Gupta Riddhi D, Paul Thomas V

机构信息

Department of Endocrinology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

Department of Clinical Microbiology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.

出版信息

J Family Med Prim Care. 2020 Jan 28;9(1):432-434. doi: 10.4103/jfmpc.jfmpc_933_19. eCollection 2020 Jan.

DOI:10.4103/jfmpc.jfmpc_933_19
PMID:32110632
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7014895/
Abstract

Fever as an indicator of disease has always been and remains a clinical symptom of great importance. It may be a manifestation of any inflammatory process of the thyroid and also may be presenting feature of thyroid storm. Melioidosis, is an infection caused by the gram negative bacterium Burkholderia pseudomallei and the commonest co-morbidity observed in India is diabetes mellitus. Here we present a case of Graves disease (hyperthyroidism) who was referred by primary care physician with history of prolonged fever of more than one month duration and later diagnosed to have melioidosis. It is important in primary care setting as family physicians need to be aware of this infection as it can affect many organs and early diagnosis and treatment will result in cure of this condition.

摘要

发热作为疾病的一个指标一直以来且仍然是一个非常重要的临床症状。它可能是甲状腺任何炎症过程的一种表现,也可能是甲状腺危象的首发特征。类鼻疽是由革兰氏阴性菌伯克霍尔德菌引起的一种感染,在印度观察到的最常见的合并症是糖尿病。在此,我们报告一例格雷夫斯病(甲状腺功能亢进症)患者,该患者由初级保健医生转诊,有持续一个多月的长期发热病史,后来被诊断为类鼻疽。在初级保健环境中这很重要,因为家庭医生需要了解这种感染,因为它可影响许多器官,早期诊断和治疗将使这种疾病得以治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6af1/7014895/fa6b093cbcb9/JFMPC-9-432-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6af1/7014895/9d303845f00f/JFMPC-9-432-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6af1/7014895/fa6b093cbcb9/JFMPC-9-432-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6af1/7014895/9d303845f00f/JFMPC-9-432-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6af1/7014895/fa6b093cbcb9/JFMPC-9-432-g002.jpg

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本文引用的文献

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Melioidosis.类鼻疽
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The cost-effectiveness of the use of selective media for the diagnosis of melioidosis in different settings.不同情况下使用选择性培养基诊断类鼻疽的成本效益。
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Clinical Manifestations, Antimicrobial Drug Susceptibility Patterns, and Outcomes in Melioidosis Cases, India.印度类鼻疽病例的临床表现、抗菌药物药敏模式和转归。
Emerg Infect Dis. 2019 Feb;25(2):316-320. doi: 10.3201/eid2502.170745.
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Melioidosis in South Asia (India, Nepal, Pakistan, Bhutan and Afghanistan).南亚(印度、尼泊尔、巴基斯坦、不丹和阿富汗)的类鼻疽病。
Trop Med Infect Dis. 2018 May 22;3(2):51. doi: 10.3390/tropicalmed3020051.
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Trop Med Infect Dis. 2018 Feb 27;3(1):25. doi: 10.3390/tropicalmed3010025.
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Melioidosis in southern India: epidemiological and clinical profile.印度南部类鼻疽病:流行病学和临床概况。
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Comparison of imipenem and ceftazidime as therapy for severe melioidosis.亚胺培南与头孢他啶治疗重症类鼻疽的比较。
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