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Dermatomyositis: a debilitating paraneoplastic phenomenon following a diagnosis of localised squamous cell carcinoma of the cervix.皮肌炎:诊断为局限性宫颈鳞状细胞癌后出现的一种使人虚弱的副肿瘤现象。
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J Am Acad Dermatol. 2020 Feb;82(2):267-281. doi: 10.1016/j.jaad.2019.06.1309. Epub 2019 Jul 4.
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Increased risk of coronary heart disease among patients with idiopathic inflammatory myositis: a nationwide population study in Taiwan.特发性炎性肌病患者患冠心病的风险增加:台湾一项全国性人群研究。
Rheumatology (Oxford). 2019 Nov 1;58(11):1935-1941. doi: 10.1093/rheumatology/kez076.
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Paraneoplastic syndromes: Definitions, classification, pathophysiology and principles of treatment.副肿瘤综合征:定义、分类、病理生理学和治疗原则。
Semin Diagn Pathol. 2019 Jul;36(4):204-210. doi: 10.1053/j.semdp.2019.01.002. Epub 2019 Feb 1.
4
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An Bras Dermatol. 2018 Jul-Aug;93(4):576-578. doi: 10.1590/abd1806-4841.20187353.
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Cardiovascular and cerebrovascular comorbidities of juvenile dermatomyositis in US children: an analysis of the National Inpatient Sample.美国儿童青少年皮肌炎的心血管和脑血管合并症:国家住院患者样本分析。
Rheumatology (Oxford). 2018 Apr 1;57(4):694-702. doi: 10.1093/rheumatology/kex465.
6
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Cardiovascular involvement in myositis.肌炎的心血管受累。
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Subclinical Cardiac Dysfunction in Polymyositis and Dermatomyositis: A Speckle-tracking Case-control Study.多肌炎和皮肌炎中的亚临床心脏功能障碍:一项斑点追踪病例对照研究
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Cardiac involvement in adult and juvenile idiopathic inflammatory myopathies.成人及青少年特发性炎性肌病的心脏受累情况。
RMD Open. 2016 Sep 27;2(2):e000291. doi: 10.1136/rmdopen-2016-000291. eCollection 2016.
10
HPV and Cervical Cancer Epidemiology - Current Status of HPV Vaccination in India.人乳头瘤病毒与宫颈癌流行病学——印度人乳头瘤病毒疫苗接种现状
Asian Pac J Cancer Prev. 2016;17(8):3663-73.

以心力衰竭为表现的皮肌炎揭示了隐匿性宫颈恶性肿瘤:一种罕见的临床关联。

Dermatomyositis presenting as heart failure revealed a concealed cervical malignancy: an infrequent clinical nexus.

作者信息

Ghosh Ritwik, Dubey Souvik, Chatterjee Subhankar, Biswas Rakesh

机构信息

Department of General Medicine, Burdwan Medical College and Hospital, Burdwan, West Bengal, India.

Department of Neuromedicine, Bangur Institute of Neurosciences, Institute of Post Graduate Medical Education and Research & SSKM Hospital, Kolkata, West Bengal, India.

出版信息

BMJ Case Rep. 2020 Feb 28;13(2):e232770. doi: 10.1136/bcr-2019-232770.

DOI:10.1136/bcr-2019-232770
PMID:32111708
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7050313/
Abstract

Dermatomyositis (DM) belongs to the spectrum of inflammatory myopathies which are a heterogeneous group of acquired disorders in which dysregulated immune system is thought to play a major pathologic role. Patients with DM generally present with characteristic skin manifestations with or without muscle weakness and pain. Although subclinical myocardial involvement in DM is well reported in literature, heart failure (HF) as its principal manifestation is extremely rare. Recognition of DM, a known paraneoplastic syndrome, should prompt clinicians to search for underlying malignancy. While gynaecological malignancies are common in association with DM, cervical cancer has rarely been heard of as an aetiology of paraneoplastic DM. We are reporting a case of DM in a postmenopausal woman presenting with advanced decompensated congestive HF with hidden squamous cell carcinoma of cervix.

摘要

皮肌炎(DM)属于炎性肌病范畴,炎性肌病是一组异质性的后天性疾病,其中免疫系统失调被认为起主要病理作用。DM患者通常表现为特征性皮肤表现,伴有或不伴有肌肉无力和疼痛。尽管文献中已充分报道DM存在亚临床心肌受累情况,但其以心力衰竭(HF)为主要表现极为罕见。认识到DM这一已知的副肿瘤综合征,应促使临床医生寻找潜在的恶性肿瘤。虽然妇科恶性肿瘤常与DM相关,但很少听说宫颈癌是副肿瘤性DM的病因。我们报告一例绝经后女性DM病例,该患者表现为晚期失代偿性充血性HF,同时伴有隐匿性宫颈鳞状细胞癌。