韩国儿童癌症幸存者中流感的发病率：一项基于人群的回顾性分析。
Incidence of Influenza Among Childhood Cancer Survivors in South Korea: A Population-based Retrospective Analysis.
机构信息
Department of Radiation Oncology, Ajou University School of Medicine, Suwon, Republic of Korea.
Department of Pediatrics, Ajou University School of Medicine, Suwon, Republic of Korea.
出版信息
In Vivo. 2020 Mar-Apr;34(2):929-933. doi: 10.21873/invivo.11860.
BACKGROUND/AIM: We quantified the incidence, and identified risk factors for influenza infection among childhood cancer survivors in South Korea, an at-risk population.
PATIENTS AND METHODS
Nationwide health insurance claims data were used to assess the frequency of influenza among childhood cancer survivors (aged <20 years) diagnosed between January 2009 and April 2016. A multivariable logistic regression was constructed to identify risk factors for influenza.
RESULTS
Of 6,457 children cancer survivors, 1,704 (27.0%) were diagnosed with influenza. Influenza was common in children <5 years old and infections were highest between late October and April. Over 60% of influenza treatment claims came from private clinics. Risk factors for influenza included age <9 years.
CONCLUSION
Childhood cancer survivors are particularly at-risk for influenza infection during the traditional influenza season. Identifying risks for influenza infection will help to establish countermeasures for reducing the influenza infections in at-risk cancer surviving children.
背景/目的：我们量化了韩国儿童癌症幸存者（高危人群）中流感感染的发生率，并确定了其感染的危险因素。
患者和方法
我们使用全国性健康保险索赔数据评估了 2009 年 1 月至 2016 年 4 月间诊断出的<20 岁的儿童癌症幸存者（年龄<20 岁）中流感的发生频率。构建了多变量逻辑回归模型，以确定流感的危险因素。
结果
在 6457 名儿童癌症幸存者中，有 1704 名（27.0%）被诊断患有流感。<5 岁的儿童中流感很常见，感染高峰期在 10 月底至 4 月之间。超过 60%的流感治疗索赔来自私人诊所。流感的危险因素包括年龄<9 岁。
结论
儿童癌症幸存者在传统流感季节特别容易感染流感。确定流感感染的风险因素将有助于制定针对高危癌症幸存儿童的流感感染预防措施。
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