The Ashe Street Clinic, Tralee, Co Kerry, Ireland.
Ir J Med Sci. 2020 Nov;189(4):1183-1187. doi: 10.1007/s11845-020-02188-5. Epub 2020 Feb 29.
Basal cell carcinoma (BCC) is a very common skin cancer in Caucasians. Although rarely life-threatening, it can be locally destructive and consumes a considerable amount of health expenditure. Treatments that are safe, cost-effective and can be carried out in primary care with a high cure rate and good cosmetic results for selected cases of BCC need to be explored.
This retrospective study was carried out to assess whether cryosurgery is a reasonable option for treating select cases of basal cell carcinomas (BCCs) in primary care under local anaesthetic by an expert cryosurgeon.
The treatment and outcome of 184 consecutive, histologically diagnosed BCCs in 138 patients in one primary care setting over a 5-year period was analysed.
One hundred (54%) BCCs were treated with cryosurgery, 57 (31%) treated by excision in primary care, 13 (7%) by photodynamic therapy (PDT), 12 (7%) by referral to plastic surgery mostly for flaps or grafts and 2 (1%) by imiquimod 5%.
Just over half of all BCCs in this survey were treated using cryosurgery (100 = 54%) and 79 were followed up for more than 5 years. The cure rate with cryosurgery was 95% after 5 years (95% CI, 0.8686-0.9837) with an excellent or good cosmetic outcome in 92%.
基底细胞癌(BCC)是白种人中非常常见的皮肤癌。虽然它很少危及生命,但它可能具有局部破坏性,并消耗大量的健康支出。需要探索安全、具有成本效益且可以在初级保健中进行、治愈率高且对选定的 BCC 病例具有良好美容效果的治疗方法。
本回顾性研究旨在评估在局部麻醉下,由冷冻治疗专家在初级保健中是否可以对选定的基底细胞癌(BCC)病例进行冷冻治疗。
分析了在一个初级保健环境中,5 年内 138 名患者的 184 例连续、组织学诊断为 BCC 的治疗和结果。
100 例(54%)BCC 采用冷冻治疗,57 例(31%)在初级保健中采用切除治疗,13 例(7%)采用光动力疗法(PDT)治疗,12 例(7%)转至整形外科治疗,主要采用皮瓣或移植物,2 例(1%)采用咪喹莫特 5%治疗。
在这项调查中,超过一半的 BCC 采用冷冻治疗(100=54%),79 例随访时间超过 5 年。冷冻治疗 5 年后的治愈率为 95%(95%CI,0.8686-0.9837),92%的病例美容效果极佳或良好。