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[自发性颅内血肿内科并发症的发生率与预后]

[Incidence and prognosis of internal medicine complications in spontaneous intracranial hematomas].

作者信息

Spitzer K, Thie A, Kunze K

机构信息

Neurologische Universitätsklinik, Hamburg-Eppendorf.

出版信息

Nervenarzt. 1988 Nov;59(11):647-53.

PMID:3211245
Abstract

The records of 133 consecutive patients with spontaneous intracranial hemorrhage were reviewed to assess the frequency of systemic complications and their influence on outcome and neurological complications. The mean age of 63 patients with spontaneous intracerebral hemorrhage (ICH) was 11 years higher compared to 70 patients with spontaneous subarachnoid hemorrhage (SAH). Concomitant disease was more frequent in ICH than in SAH, and general atherosclerosis, chronic obstructive pulmonary disease and cardiac failure were associated with an increased mortality. 94% of all ICH and 79% of all SAH patients developed at least one systemic complication. A correlation was found between initial and late hyperglycemia, and high mortality rate and poor survival quality. In both groups an association of cardiac arrhythmias with intracranial pressure and an unfavourable outcome were observed. SAH patients with QT-prolongation had an increase in mortality and developed ischemic deficits more frequently. Pulmonary complications and disturbances of blood pressure regulation were associated with an unfavourable outcome, and in SAH patients with occurrence of neurologic complications.

摘要

回顾了133例连续的自发性颅内出血患者的记录,以评估全身并发症的发生率及其对预后和神经并发症的影响。63例自发性脑出血(ICH)患者的平均年龄比70例自发性蛛网膜下腔出血(SAH)患者高11岁。ICH患者合并症比SAH患者更常见,全身性动脉粥样硬化、慢性阻塞性肺疾病和心力衰竭与死亡率增加相关。所有ICH患者中有94%和所有SAH患者中有79%至少发生一种全身并发症。发现初始和晚期高血糖之间存在相关性,且死亡率高和生存质量差。在两组中均观察到心律失常与颅内压及不良预后之间存在关联。QT间期延长的SAH患者死亡率增加,且更频繁地出现缺血性缺损。肺部并发症和血压调节紊乱与不良预后相关,且在发生神经并发症的SAH患者中也是如此。

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