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孔雀草的传统用途、植物化学和药理学活性

Traditional uses, Phyto-chemistry and pharmacological activities of Tagetes Patula L.

机构信息

Department of Pharmacy, Shaheed Benazir Bhutto University, Sheringal Dir (U), 18050, Pakistan.

Natural Products and Alternative Medicines, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

出版信息

J Ethnopharmacol. 2020 Jun 12;255:112718. doi: 10.1016/j.jep.2020.112718. Epub 2020 Feb 27.

DOI:10.1016/j.jep.2020.112718
PMID:32112898
Abstract

ETHNO-PHARMACOLOGICAL RELEVANCE: Tagetes patula L. an important medicinal plant of Asteraceae family is worldwide distributed and reported for its folkloric use in various disorders like skin, eye problems, injury and stomach issues by different communities of China, Nepal, India, Bangladesh and Pakistan.

AIM OF THIS REVIEW

The present review has focused the ethnomedicinal and traditional uses of T. patula with special reference to Asian countries. Chemical constituents and pharmacological aspects of T. patula was explored. After reading the review the researchers may able to find new insights to further investigate this plant.

REVISION OF LITERATURE

Google scholar, PubMed, and Science direct, were the major search engines used to get relevant information based on articles and books.

RESULTS

and Discussion: The ethno-botanical aspects were recorded, the pharmacological aspects like antioxidant, anti-inflammatory, antimicrobial, anti-parasitic and anti-diabetic potentials evaluated both in vivo and in vitro is described. The toxicity or allergic manifestation with the use of the plant is also a section in the article. It is a rich source for thiophene derivatives, flavonoids, carotenoids, terpenes and terpenoids. Various gaps were pointed out for researchers that need to be investigated.

CONCLUSION

Various traditional uses have been reported in Asian countries that need to be scientifically investigated in depth and several pharmacological activities have been reported for the T. patula but more detailed and mechanism-based studies linked to a particular lead compound need to be targeted in future.

摘要

民族药理学相关性

万寿菊(Tagetes patula L.)是菊科的一种重要药用植物,分布广泛,据报道,在中国、尼泊尔、印度、孟加拉国和巴基斯坦等不同社区,它具有民间用途,可以治疗各种疾病,如皮肤、眼睛问题、损伤和胃部问题。

目的

本综述重点关注了万寿菊的民族医学用途和传统用途,特别是在亚洲国家。还探讨了万寿菊的化学成分和药理学方面。阅读完这篇综述后,研究人员可能能够找到新的见解,以进一步研究这种植物。

文献综述

主要使用 Google 学术、PubMed 和 Science Direct 等搜索引擎,根据文章和书籍获取相关信息。

结果与讨论

记录了民族植物学方面的信息,描述了抗氧化、抗炎、抗菌、抗寄生虫和抗糖尿病等药理学方面的潜力,包括体内和体外评估。文章中还介绍了使用该植物的毒性或过敏表现。它是噻吩衍生物、类黄酮、类胡萝卜素、萜类和萜烯类化合物的丰富来源。指出了研究人员需要调查的各种差距。

结论

亚洲国家报告了各种传统用途,需要进行深入的科学研究,并且已经报道了万寿菊的几种药理学活性,但需要针对特定的先导化合物进行更详细和基于机制的研究。

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