Siriraj Health Technology Assessment Unit, Siriraj Hospital, Mahidol University, Bangkok, Thailand; Pharmacy Department, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Siriraj Health Technology Assessment Unit, Siriraj Hospital, Mahidol University, Bangkok, Thailand; Pharmacy Department, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Value Health Reg Issues. 2020 May;21:194-200. doi: 10.1016/j.vhri.2019.12.001. Epub 2020 Feb 26.
This study aimed to compare the EuroQol 5-dimension 5-level questionnaire (EQ-5D-5L), the visual analogue scale (VAS), and the Kidney Disease Quality of Life 36-Item Short-Form Survey (KDQOL-36) scores of Thai continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) patients and to compare the utility scores with the EQ-5D-5L and VAS scores of caregivers.
This was a cross-sectional study completed between April 2016 and May 2017. In total, 34 CAPD patients, 30 APD patients, and their caregivers were recruited from a large university hospital in Thailand. A trained interviewer conducted face-to-face interviews. We collected demographic data and used the KDQOL-36 and EuroQol questionnaires (EQ-5D-5L and VAS) to assess the health-related quality of life. Caregivers were asked to assess their own health status using the EQ-5D-5L and VAS.
The EQ-5D-5L and VAS responses of the CAPD and APD patients and their caregivers were not significantly different (P > .05). More than 50% of both patient groups had mobility problems, whereas most patients had no problems with self-care, doing usual activities, pain or discomfort, and anxiety or depression. As for the KDQOL-36, the physical and mental component summaries were not significantly different, and neither were the scores for all of the kidney disease-specific dimensions, including symptoms or problems, effects of kidney disease, and burden of kidney disease (all were P > .05).
The results indicated that the quality of life of CAPD and APD patients and their caregivers were mostly equivalent. A further longitudinal study of utility score assessments of the differences in modality would be advantageous.
本研究旨在比较泰国持续非卧床腹膜透析（CAPD）和自动化腹膜透析（APD）患者的欧洲五维健康量表 5 维问卷（EQ-5D-5L）、视觉模拟量表（VAS）和肾脏病生活质量 36 项简表（KDQOL-36）评分，并比较效用评分与 EQ-5D-5L 和 VAS 评分的差异。
这是一项横断面研究，于 2016 年 4 月至 2017 年 5 月进行。共招募了来自泰国一家大型大学医院的 34 名 CAPD 患者、30 名 APD 患者及其护理人员。一名经过培训的访谈员进行了面对面的访谈。我们收集了人口统计学数据，并使用 KDQOL-36 和欧洲五维健康量表问卷（EQ-5D-5L 和 VAS）评估了健康相关生活质量。护理人员被要求使用 EQ-5D-5L 和 VAS 评估自己的健康状况。
CAPD 和 APD 患者及其护理人员的 EQ-5D-5L 和 VAS 反应无显著差异（P>.05）。两组患者均有超过 50%的患者存在行动问题，而大多数患者在自我护理、日常活动、疼痛或不适以及焦虑或抑郁方面均不存在问题。就 KDQOL-36 而言，生理和心理成分综合评分无显著差异，所有肾脏病特异性维度的评分也无显著差异，包括症状或问题、肾脏病影响以及肾脏病负担（均 P>.05）。
结果表明，CAPD 和 APD 患者及其护理人员的生活质量大多相当。进一步对不同治疗方式的效用评分评估进行纵向研究将是有益的。
