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肾脏病特定评分和连续不卧床腹膜透析及自动化腹膜透析患者及其照护者的健康效用。

Kidney Disease-Specific Scores and Health Utility of Continuous Ambulatory Peritoneal Dialysis and Automated Peritoneal Dialysis Patients and Their Caregivers.

机构信息

Siriraj Health Technology Assessment Unit, Siriraj Hospital, Mahidol University, Bangkok, Thailand; Pharmacy Department, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Siriraj Health Technology Assessment Unit, Siriraj Hospital, Mahidol University, Bangkok, Thailand; Pharmacy Department, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Value Health Reg Issues. 2020 May;21:194-200. doi: 10.1016/j.vhri.2019.12.001. Epub 2020 Feb 26.

Abstract

OBJECTIVES

This study aimed to compare the EuroQol 5-dimension 5-level questionnaire (EQ-5D-5L), the visual analogue scale (VAS), and the Kidney Disease Quality of Life 36-Item Short-Form Survey (KDQOL-36) scores of Thai continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) patients and to compare the utility scores with the EQ-5D-5L and VAS scores of caregivers.

METHODS

This was a cross-sectional study completed between April 2016 and May 2017. In total, 34 CAPD patients, 30 APD patients, and their caregivers were recruited from a large university hospital in Thailand. A trained interviewer conducted face-to-face interviews. We collected demographic data and used the KDQOL-36 and EuroQol questionnaires (EQ-5D-5L and VAS) to assess the health-related quality of life. Caregivers were asked to assess their own health status using the EQ-5D-5L and VAS.

RESULTS

The EQ-5D-5L and VAS responses of the CAPD and APD patients and their caregivers were not significantly different (P > .05). More than 50% of both patient groups had mobility problems, whereas most patients had no problems with self-care, doing usual activities, pain or discomfort, and anxiety or depression. As for the KDQOL-36, the physical and mental component summaries were not significantly different, and neither were the scores for all of the kidney disease-specific dimensions, including symptoms or problems, effects of kidney disease, and burden of kidney disease (all were P > .05).

CONCLUSIONS

The results indicated that the quality of life of CAPD and APD patients and their caregivers were mostly equivalent. A further longitudinal study of utility score assessments of the differences in modality would be advantageous.

摘要

目的

本研究旨在比较泰国持续非卧床腹膜透析(CAPD)和自动化腹膜透析(APD)患者的欧洲五维健康量表 5 维问卷(EQ-5D-5L)、视觉模拟量表(VAS)和肾脏病生活质量 36 项简表(KDQOL-36)评分,并比较效用评分与 EQ-5D-5L 和 VAS 评分的差异。

方法

这是一项横断面研究,于 2016 年 4 月至 2017 年 5 月进行。共招募了来自泰国一家大型大学医院的 34 名 CAPD 患者、30 名 APD 患者及其护理人员。一名经过培训的访谈员进行了面对面的访谈。我们收集了人口统计学数据,并使用 KDQOL-36 和欧洲五维健康量表问卷(EQ-5D-5L 和 VAS)评估了健康相关生活质量。护理人员被要求使用 EQ-5D-5L 和 VAS 评估自己的健康状况。

结果

CAPD 和 APD 患者及其护理人员的 EQ-5D-5L 和 VAS 反应无显著差异(P>.05)。两组患者均有超过 50%的患者存在行动问题,而大多数患者在自我护理、日常活动、疼痛或不适以及焦虑或抑郁方面均不存在问题。就 KDQOL-36 而言,生理和心理成分综合评分无显著差异,所有肾脏病特异性维度的评分也无显著差异,包括症状或问题、肾脏病影响以及肾脏病负担(均 P>.05)。

结论

结果表明,CAPD 和 APD 患者及其护理人员的生活质量大多相当。进一步对不同治疗方式的效用评分评估进行纵向研究将是有益的。

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