[Changes in the protein spectrum of human kidney anlagen].

Extracts of metanephros were studied using two-dimensional electrophoresis in human embryos at the age of 7 to 21 week of intrauterine development. Electrophoregrams show 160 to 190 protein fractions. Fractions have been identified which corresponded to actin, albumin, alpha-chain of tropomyosin, light chains of myosin. The tropomyosin zone fractions were subject to greatest changes during development. Other zones of the embryonic kidney electrophoretogram displayed, predominantly, quantitative changes of polypeptides.