• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

评估精神分裂症患者中强迫症共病和强迫症状维度。

Assessment of obsessive-compulsive disorder comorbidity and obsessive-compulsive symptom dimensions in patients with schizophrenia.

机构信息

Department of Psychiatry, Faculty of Medicine, Health Sciences University, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey. E-mail.

出版信息

Saudi Med J. 2020 Mar;41(3):275-282. doi: 10.15537/smj.2020.3.24909.

DOI:10.15537/smj.2020.3.24909
PMID:32114600
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7841571/
Abstract

OBJECTIVES

To assess obsessive-compulsive disorder (OCD) comorbidity and obsessive-compulsive symptom (OCS) dimensions in patients with schizophrenia.

METHODS

This cross-sectional study included 300 patients with schizophrenia who were applied to the to the Outpatient Psychiatry Clinic of Health Sciences University Dışkapı Yıldırım Beyazıt Training and Research Hospital,  Ankara, Turkey between July and December 2018. Data collection forms created by researchers were applied to the individuals. Obsessive-compulsive symptom were assessed with the Yale-Brown Obsessive Compulsive Scale (YBOCS) and the Dimensional Obsessive Compulsive Scale (DOCS).

RESULTS

The OCD prevalence was 17% (n=50) in the whole group while 10% (n=24/250) of the patients without OCD had 8-15 points at YBOCS. One-way ANOVA test revealed that the patients with OCD showed more severe positive, negative, and depressive symptoms, and also had lower functionality compared to those without OCD (p less than 0.05). The most severe OCS dimension was unacceptable obsessional thoughts in the patients with OCD and OCS. The severity of unacceptable obsessional thoughts was positively correlated with the depressive symptom severity, and negatively correlated with onset age of OCD and insight level in Pearson correlation analysis.

CONCLUSION

Patients with schizophrenia should be evaluated for presence of the OCS/OCD comorbidity in clinical practice. In addition, dimensional assessment of OCS might provide a different viewpoint on the presence of OCS/OCD in schizophrenia.

摘要

目的

评估精神分裂症患者中强迫症(OCD)共病和强迫症状(OCS)维度。

方法

本横断面研究纳入了 2018 年 7 月至 12 月期间在土耳其安卡拉卫生科学大学 Dışkapı Yıldırım Beyazıt 培训与研究医院门诊精神病学诊所就诊的 300 名精神分裂症患者。研究人员制定的数据采集表用于评估患者。使用耶鲁-布朗强迫量表(YBOCS)和多维强迫量表(DOCS)评估强迫症状。

结果

全组 OCD 患病率为 17%(n=50),而无 OCD 的患者中有 10%(n=24/250)在 YBOCS 上得分为 8-15 分。单因素方差分析显示,与无 OCD 的患者相比,患有 OCD 的患者表现出更严重的阳性、阴性和抑郁症状,且功能更差(p<0.05)。在患有 OCD 和 OCS 的患者中,最严重的 OCS 维度是无法接受的强迫性思维。不可接受的强迫性思维的严重程度与抑郁症状的严重程度呈正相关,与 OCD 的发病年龄和 Pearson 相关分析中的洞察力水平呈负相关。

结论

在临床实践中,应评估精神分裂症患者是否存在 OCS/OCD 共病。此外,OCS 的维度评估可能为精神分裂症中存在 OCS/OCD 提供不同的视角。

相似文献

1
Assessment of obsessive-compulsive disorder comorbidity and obsessive-compulsive symptom dimensions in patients with schizophrenia.评估精神分裂症患者中强迫症共病和强迫症状维度。
Saudi Med J. 2020 Mar;41(3):275-282. doi: 10.15537/smj.2020.3.24909.
2
The 5-year course of obsessive-compulsive symptoms and obsessive-compulsive disorder in first-episode schizophrenia and related disorders.首发精神分裂症及相关障碍患者中强迫症状和强迫症的 5 年病程。
Schizophr Bull. 2013 Jan;39(1):151-60. doi: 10.1093/schbul/sbr077. Epub 2011 Jul 28.
3
Obsessive-compulsive disorder and obsessive-compulsive symptoms in Japanese inpatients with chronic schizophrenia - a possible schizophrenic subtype.慢性精神分裂症住院日本患者的强迫症和强迫症状——可能的精神分裂症亚型。
Psychiatry Res. 2010 Oct 30;179(3):241-6. doi: 10.1016/j.psychres.2009.08.003. Epub 2010 May 18.
4
Obsessive compulsive symptoms are related to lower quality of life in patients with Schizophrenia.强迫症症状与精神分裂症患者较低的生活质量相关。
Int J Psychiatry Clin Pract. 2014 Oct;18(4):243-7. doi: 10.3109/13651501.2014.943243. Epub 2014 Aug 26.
5
Prevalence and clinical correlates of obsessive-compulsive disorder in schizophrenia.精神分裂症中强迫症的患病率及其临床相关因素
Compr Psychiatry. 2015 Jan;56:141-8. doi: 10.1016/j.comppsych.2014.09.015. Epub 2014 Sep 20.
6
Obsessive compulsive disorder and symptoms may have different effects on schizophrenia.强迫症和症状可能对精神分裂症有不同的影响。
Prog Neuropsychopharmacol Biol Psychiatry. 2011 Mar 30;35(2):429-33. doi: 10.1016/j.pnpbp.2010.08.021. Epub 2010 Sep 8.
7
Polygenetic risk scores and phenotypic constellations of obsessive-compulsive disorder in clozapine-treated schizophrenia.氯氮平治疗精神分裂症中强迫症的多基因风险评分和表型组合。
Eur Arch Psychiatry Clin Neurosci. 2024 Feb;274(1):181-193. doi: 10.1007/s00406-023-01593-y. Epub 2023 Apr 5.
8
Obsessive-compulsive symptom dimensions in schizophrenia patients with comorbid obsessive-compulsive disorder.精神分裂症合并强迫症患者的强迫症状维度。
Prog Neuropsychopharmacol Biol Psychiatry. 2009 Aug 31;33(6):1009-12. doi: 10.1016/j.pnpbp.2009.05.008. Epub 2009 May 15.
9
[Dimensional Approach to Obsessive-Compulsive Disorder: Dimensional Obsessive-Compulsive Scale with Turkish Psychometric Properties].[强迫症的维度研究方法:具有土耳其心理测量特性的维度强迫症量表]
Turk Psikiyatri Derg. 2018 Summer;29(2):122-130.
10
Comparison of clinical characteristics, co-morbidity and pharmacotherapy in adolescent schizophrenia patients with and without obsessive-compulsive disorder.有和没有强迫症的青少年精神分裂症患者的临床特征、合并症及药物治疗比较
Psychiatry Res. 2008 May 30;159(1-2):133-9. doi: 10.1016/j.psychres.2007.06.010. Epub 2008 Apr 11.

引用本文的文献

1
Different degrees of nodes behind obsessive-compulsive symptoms of schizophrenia.精神分裂症强迫症状背后不同程度的节点。
Front Psychiatry. 2023 Jul 27;14:1224040. doi: 10.3389/fpsyt.2023.1224040. eCollection 2023.
2
Impact of COVID-19 Pandemic on Prescribing of Long-Acting Injectable Antipsychotics for Schizophrenia: Results from a United States Prescriber Survey.新冠疫情对精神分裂症长效注射用抗精神病药物处方的影响:一项美国处方医生调查结果
Neuropsychiatr Dis Treat. 2022 Sep 7;18:2003-2019. doi: 10.2147/NDT.S379985. eCollection 2022.

本文引用的文献

1
A cross sectional study of impact and clinical risk factors of antipsychotic-induced OCD.抗精神病药物所致强迫症的影响因素及临床危险因素的横断面研究
Eur Neuropsychopharmacol. 2019 Aug;29(8):905-913. doi: 10.1016/j.euroneuro.2019.06.006. Epub 2019 Jul 11.
2
Obsessive-Compulsive Symptoms in Schizophrenia: an Up-To-Date Review of Literature.精神分裂症中的强迫症状:文献的最新综述。
Curr Psychiatry Rep. 2019 Jul 1;21(8):64. doi: 10.1007/s11920-019-1051-y.
3
Risk of schizophrenia among people with obsessive-compulsive disorder: A nationwide population-based cohort study.强迫症患者患精神分裂症的风险:一项全国范围内基于人群的队列研究。
Schizophr Res. 2019 Jul;209:58-63. doi: 10.1016/j.schres.2019.05.024. Epub 2019 May 24.
4
Schizophrenia-spectrum psychopathology in obsessive-compulsive disorder: an empirical study.强迫症中精神分裂症谱系的精神病理学:一项实证研究。
Eur Arch Psychiatry Clin Neurosci. 2020 Dec;270(8):993-1002. doi: 10.1007/s00406-019-01022-z. Epub 2019 May 25.
5
Schizophrenia and co-morbid obsessive - compulsive disorder: Clinical characteristics.精神分裂症及合并强迫症:临床特征。
Asian J Psychiatr. 2018 Oct;37:80-84. doi: 10.1016/j.ajp.2018.08.016. Epub 2018 Aug 18.
6
Distinct risk factors for obsessive and compulsive symptoms in chronic schizophrenia.慢性精神分裂症中强迫和强迫症状的不同危险因素。
Psychol Med. 2018 Dec;48(16):2668-2675. doi: 10.1017/S003329171800017X. Epub 2018 Feb 19.
7
Mapping Compulsivity in the DSM-5 Obsessive Compulsive and Related Disorders: Cognitive Domains, Neural Circuitry, and Treatment.DSM-5 强迫及相关障碍中的强迫映射:认知领域、神经回路和治疗。
Int J Neuropsychopharmacol. 2018 Jan 1;21(1):42-58. doi: 10.1093/ijnp/pyx088.
8
Obsessive Compulsive Symptoms/disorder in patients with schizophrenia: Prevalence, relationship with other symptom dimensions and impact on functioning.精神分裂症患者的强迫症状/障碍:患病率、与其他症状维度的关系及其对功能的影响。
Psychiatry Res. 2017 Apr;250:277-284. doi: 10.1016/j.psychres.2017.01.067. Epub 2017 Jan 25.
9
Antipsychotic augmentation vs. monotherapy in schizophrenia: systematic review, meta-analysis and meta-regression analysis.抗精神病药物增效治疗与单一疗法治疗精神分裂症的比较:系统评价、荟萃分析和元回归分析
World Psychiatry. 2017 Feb;16(1):77-89. doi: 10.1002/wps.20387.
10
Obsessive-compulsive symptoms and overall psychopathology in psychotic disorders: longitudinal assessment of patients and siblings.精神病性障碍患者及患者同胞的强迫症状与总体精神病理学:纵向评估
Eur Arch Psychiatry Clin Neurosci. 2018 Apr;268(3):279-289. doi: 10.1007/s00406-016-0751-0. Epub 2016 Dec 17.