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基于医院的横断面研究:糖尿病患者中未控制高血压的患病率、危险因素和管理。

Prevalence, risk factors, and management of uncontrolled hypertension among patients with diabetes: A hospital-based cross-sectional study.

机构信息

Department of Clinical Pharmacy, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Riyadh, 11942, Saudi Arabia.

College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Riyadh, 11942, Saudi Arabia.

出版信息

Prim Care Diabetes. 2020 Dec;14(6):610-615. doi: 10.1016/j.pcd.2020.02.004. Epub 2020 Feb 27.

Abstract

AIMS

This research examines the prevalence of uncontrolled hypertension and associated risk factors among patients with diabetes in Saudi Arabia.

METHODS

A hospital-based, cross-sectional study was used in patients with diabetes and hypertension attending outpatient diabetes clinics in King Khaled Hospital and Prince Sultan Center for Health Care in Al-Kharj, Riyadh. Patients' information, data on hypertension, type of treatment, and comorbidities were captured through electronic medical records. Uncontrolled hypertension was defined as blood pressure (BP) measurements greater than or equal to 140/90 mmHg. Antihypertensive medication use among these patients was analyzed. Multivariate analysis was performed to detect the associated factors of uncontrolled hypertension.

RESULTS

Of 1178 outpatients‬ with diabetes who were included in the study sample, uncontrolled hypertension presented in 846 (71.8%). Most patients were on two antihypertensive medications, and the most frequently used was calcium channel blockers, followed by angiotensin-converting enzyme inhibitors. Individuals most likely to have uncontrolled hypertension were those older than 65 years (OR 1.99, 95%CI: 1.059, 3.77), male (OR = 1.51, 95%CI: 1.031, 2.22), and obese (OR = 2.39, 95%CI: 1.63, 3.504), with two (OR = 3.894, 95% CI: 2.481, 6.114) or three or more comorbidities (OR = 4.020, 95% CI: 2.510, 6.439), and with polypharmacy (OR = 1.814, 95% CI: 1.238, 2.656).

CONCLUSION

The extent of uncontrolled hypertension among patients with diabetes in the study sample was found to be high. Age, sex, obesity, number of comorbidities, and polypharmacy are the most important correlates with increased risk of uncontrolled hypertension.

摘要

目的

本研究旨在调查沙特阿拉伯糖尿病患者中未控制高血压的患病率及其相关危险因素。

方法

采用医院横断面研究,纳入在利雅得的哈立德国王医院和苏丹王子医疗中心的门诊糖尿病诊所就诊的糖尿病合并高血压患者。通过电子病历记录患者信息、高血压相关数据、治疗类型和合并症。将血压(BP)测量值大于或等于 140/90mmHg 定义为未控制的高血压。分析这些患者的抗高血压药物使用情况。采用多变量分析检测未控制高血压的相关因素。

结果

在纳入研究样本的 1178 名门诊患者中,有 846 名(71.8%)患有未控制的高血压。大多数患者服用两种降压药物,最常用的是钙通道阻滞剂,其次是血管紧张素转换酶抑制剂。年龄大于 65 岁(OR 1.99,95%CI:1.059,3.77)、男性(OR=1.51,95%CI:1.031,2.22)和肥胖(OR=2.39,95%CI:1.63,3.504)的个体更有可能患有未控制的高血压,同时存在两种(OR=3.894,95%CI:2.481,6.114)或三种或更多合并症(OR=4.020,95%CI:2.510,6.439)以及多药治疗(OR=1.814,95%CI:1.238,2.656)的个体也是如此。

结论

研究样本中糖尿病患者未控制高血压的程度很高。年龄、性别、肥胖、合并症数量和多药治疗是与未控制高血压风险增加最相关的重要因素。

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