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逐步推进:一种针对抑郁症的电子心理健康干预措施——来自黎巴嫩的混合方法试点研究

Step-by-Step, an E-Mental Health Intervention for Depression: A Mixed Methods Pilot Study From Lebanon.

作者信息

Harper Shehadeh Melissa Joanne, Abi Ramia Jinane, Cuijpers Pim, El Chammay Rabih, Heim Eva, Kheir Wissam, Saeed Khalid, van Ommeren Mark, Van't Hof Edith, Watts Sarah, Wenger Andreas, Zoghbi Edwina, Carswell Kenneth

机构信息

Department of Mental Health and Substance Use, World Health Organization, Geneva, Switzerland.

Institute of Global Health, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

出版信息

Front Psychiatry. 2020 Feb 12;10:986. doi: 10.3389/fpsyt.2019.00986. eCollection 2019.

Abstract

BACKGROUND

E-mental health is an established mode of delivering treatment for common mental disorders in many high income countries. However, evidence of its effectiveness in lower income countries is lacking. This mixed methods study presents lessons learned and preliminary data on the feasibility of a minimally guided e-mental health intervention in Lebanon. The aim was to pilot test Step-by-Step, a WHO guided e-mental health intervention, and research methods prior to future, controlled testing.

METHODS

Participants were recruited using social media and advertisements in primary care clinics. Participants completed baseline and post-intervention questionnaires on depression symptoms (primary outcome, PHQ-8), anxiety symptoms, well-being, disability and self-perceived problem severity, and a client satisfaction questionnaire. In addition, seven completers, four drop-outs, 11 study staff, and four clinic managers were interviewed with responses thematically analyzed. Website analytics were used to understand participant behavior when using the website.

RESULTS

A total of 129 participants signed up the Step-by-Step website. Seventy-four participants started session 1 after completing pre-test questionnaires and 26 completed both baseline and post-intervention data. Among those who completed post-assessments, depression symptoms improved (PHQ-8 scores (t=5.62, p < 0.001 two-tailed, df = 25). Wilcoxon signed ranks tests showed a significant difference between baseline and post-Step-by-Step scores on all secondary outcome measures. Client satisfaction data was positive. Interview responses suggested that the intervention could be made more appropriate for younger, single people, more motivating, and easier to use. Those who utilized the support element of the intervention were happy with their relationship with the non-specialist support person (e-helper), though some participants would have preferred specialist support. E-helpers would have liked more training on complex cases. Website analytics showed that many users dropped out before intervention start, and that some re-entered screening data having been excluded from the study.

CONCLUSION

Step-by-Step skills and techniques, model of service integration, and its non-specialist support element are acceptable. Though the sample was small and non-controlled and drop-out was high, results suggest that it may be effective in reducing depression and anxiety symptoms and increasing well-being. Lessons learned will inform content revision, the development of an app version of Step-by-Step, and the research methodology of upcoming effectiveness studies.

摘要

背景

在许多高收入国家,电子心理健康已成为治疗常见精神障碍的既定模式。然而,在低收入国家缺乏其有效性的证据。这项混合方法研究介绍了在黎巴嫩进行的最低限度指导的电子心理健康干预的经验教训和可行性的初步数据。目的是在未来进行对照试验之前,对世界卫生组织指导的电子心理健康干预措施“循序渐进”及其研究方法进行试点测试。

方法

通过社交媒体和初级保健诊所的广告招募参与者。参与者完成了关于抑郁症状(主要结果,PHQ-8)、焦虑症状、幸福感、残疾和自我感知问题严重程度的基线和干预后问卷,以及一份客户满意度问卷。此外,对7名完成者、4名退出者、11名研究人员和4名诊所经理进行了访谈,并对他们的回答进行了主题分析。使用网站分析来了解参与者使用网站时的行为。

结果

共有129名参与者注册了“循序渐进”网站。74名参与者在完成预测试问卷后开始第1节课程,26名参与者完成了基线和干预后的数据。在完成后评估的参与者中,抑郁症状有所改善(PHQ-8评分(t = 5.62,双尾p < 0.001,df = 25))。Wilcoxon符号秩检验显示,在所有次要结果指标上,基线和“循序渐进”后评分之间存在显著差异。客户满意度数据是积极的。访谈回答表明,该干预措施可以更适合年轻的单身人士,更具激励性,且更易于使用。那些利用干预措施支持部分的人对他们与非专业支持人员(电子助手)的关系感到满意,尽管一些参与者更喜欢专业支持。电子助手希望获得更多关于复杂病例的培训。网站分析表明,许多用户在干预开始前就退出了,而且一些人在被排除出研究后重新输入了筛查数据。

结论

“循序渐进”的技能和技术、服务整合模式及其非专业支持部分是可以接受的。尽管样本量小且无对照,退出率高,但结果表明它可能在减轻抑郁和焦虑症状以及提高幸福感方面有效。吸取的经验教训将为内容修订、“循序渐进”应用程序版本的开发以及即将进行的有效性研究的研究方法提供参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bde/7034323/2b8a6b12798a/fpsyt-10-00986-g001.jpg

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