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Human Disease Ontology 2018 update: classification, content and workflow expansion.人类疾病本体论 2018 更新:分类、内容和工作流程扩展。
Nucleic Acids Res. 2019 Jan 8;47(D1):D955-D962. doi: 10.1093/nar/gky1032.
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Cloud based framework for diagnosis of diabetes mellitus using K-means clustering.基于云的使用K均值聚类的糖尿病诊断框架。
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The Research of Clinical Decision Support System Based on Three-Layer Knowledge Base Model.基于三层知识库模型的临床决策支持系统研究。
J Healthc Eng. 2017;2017:6535286. doi: 10.1155/2017/6535286. Epub 2017 Jul 27.
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Mining comorbidity patterns using retrospective analysis of big collection of outpatient records.利用对大量门诊记录的回顾性分析挖掘共病模式。
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A novel data-driven workflow combining literature and electronic health records to estimate comorbidities burden for a specific disease: a case study on autoimmune comorbidities in patients with celiac disease.一种结合文献和电子健康记录以估计特定疾病合并症负担的新型数据驱动工作流程:以乳糜泻患者的自身免疫性合并症为例
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构建用于医疗健康状况分类的基于知识的异构信息图。

Constructing a knowledge-based heterogeneous information graph for medical health status classification.

作者信息

Pham Thuan, Tao Xiaohui, Zhang Ji, Yong Jianming

机构信息

University of Southern Queensland, Toowoomba, Australia.

出版信息

Health Inf Sci Syst. 2020 Feb 14;8(1):10. doi: 10.1007/s13755-020-0100-6. eCollection 2020 Dec.

DOI:10.1007/s13755-020-0100-6
PMID:32117570
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7021844/
Abstract

Applying and in building a heterogeneous information graph (HIG) to develop a classification model has achieved a notable performance in improving the accuracy of predicting the status of health risks. In this study, the approach that was used, integrated knowledge of the medical domain as well as taking advantage of applying and in building a classification model for diagnosis. The research mined knowledge which was extracted from titles and abstracts of MEDLINE to discover how to assess the links between objects relating to medical concepts. A knowledge-base HIG model then was developed for the prediction of a patient's health status. The results of the experiment showed that the knowledge-base model was superior to the baseline model and has demonstrated that the knowledge-base could help improve the performance of the classification model. The contribution of this study has been to provide a framework for applying a knowledge-base in the classification model which helps these models achieve the best performance of predictions. This study has also contributed a model to medical practice to help practitioners become more confident in making final decisions in diagnosing illness. Moreover, this study affirmed that biomedical literature could assist in building a classification model. This contribution will be advantageous for future researchers in mining the knowledge-base to develop different kinds of classification models.

摘要

在构建异构信息图(HIG)以开发分类模型时应用[具体内容缺失],在提高健康风险状态预测准确性方面取得了显著成效。在本研究中,所采用的方法整合了医学领域知识,并利用[具体内容缺失]构建诊断分类模型。该研究挖掘了从MEDLINE的标题和摘要中提取的知识,以发现如何评估与医学概念相关的对象之间的联系。然后开发了一个知识库HIG模型来预测患者的健康状况。实验结果表明,知识库模型优于基线模型,并证明知识库有助于提高分类模型的性能。本研究的贡献在于为在分类模型中应用知识库提供了一个框架,有助于这些模型实现最佳预测性能。本研究还为医学实践贡献了一个模型,帮助从业者在疾病诊断中做出最终决策时更有信心。此外,本研究证实生物医学文献有助于构建分类模型。这一贡献将有利于未来研究人员挖掘知识库以开发不同类型的分类模型。