Nicolini U, Santolaya J, Ojo O E, Fisk N M, Hubinont C, Tonge M, Rodeck C H
Royal Postgraduate Medical School, Queen Charlotte's Maternity Hospital, London, U.K.
Prenat Diagn. 1988 Nov;8(9):665-71. doi: 10.1002/pd.1970080906.
Seventy-one fetal blood samplings (FBS) were attempted from the intrahepatic portion of the umbilical vein (IHV) at 18-34 weeks; 54 were attempted primarily and 17 secondarily after a failed attempt at the placental cord insertion. Fetal blood was obtained in 89 per cent of the cases. Intravascular transfusion (IVT) was attempted on 31 occasions and successful in 24 (77 per cent). In all cases of failed sampling or transfusion via the IHV, prenatal diagnosis and/or therapy was accomplished using alternative procedures. On only one occasion was the procedure postponed. There were no losses or neonatal morbidity attributable to the procedure. FBS from the IHV may be considered as an alternative approach to sampling the placental cord insertion. It is recommended in cases where the approach to the placental cord insertion is difficult or hazardous.
在18至34周时，尝试从脐静脉肝内部分（IHV）进行71次胎儿血样采集（FBS）；54次为首次尝试，17次是在胎盘脐带插入处尝试失败后进行的二次尝试。89%的病例成功采集到胎儿血液。进行了31次血管内输血（IVT），24次成功（77%）。在所有通过IHV采样或输血失败的病例中，采用替代程序完成了产前诊断和/或治疗。仅1次手术被推迟。该手术没有导致任何损失或新生儿发病。来自IHV的FBS可被视为胎盘脐带插入处采样的替代方法。在难以或危险接近胎盘脐带插入处的情况下推荐使用。
