Chinnaiya A, Venkat A, Dawn C, Chee W Y, Choo K B, Gole L A, Meng C T
Department of Obstetrics and Gynaecology, National University Hospital, Singapore.
J Obstet Gynaecol Res. 1998 Aug;24(4):239-46. doi: 10.1111/j.1447-0756.1998.tb00083.x.
To identify the site of fetal blood sampling (FBS) with lesser complications; and also analyses the reasons for targetting the intrahepatic vein (IHV) for FBS.
Fetal blood sampling (FBS) performed on 382 women over a period of 7 years at the National University Hospital, Singapore was analysed. FBS was performed from 13 weeks of gestational age onwards. In 76.4% (292 of 382) the intrahepatic part of the umbilical vein (IHV) was targetted; in 18.3% (70 of 382) percutaneous umbilical cord sampling (PUBS) was performed; in 5.2% (20 of 382) cardiocentesis was performed to obtain fetal blood.
Multivariate analysis showed an increase in odds of fetal loss for umbilical cord and cardiocentesis groups compared with the IHV FBS group. It was statistically significant (p < 0.01) only in the cardiocentesis group for fetal loss at < 2 weeks of performing the procedure.
确定并发症较少的胎儿血样采集（FBS）部位；并分析将肝内静脉（IHV）作为FBS采血目标的原因。
对新加坡国立大学医院7年间382名女性进行的胎儿血样采集（FBS）进行分析。FBS从孕13周起进行。76.4%（382例中的292例）以脐静脉肝内部（IHV）为采血目标；18.3%（382例中的70例）进行了经皮脐血采样（PUBS）；5.2%（382例中的20例）通过心脏穿刺获取胎儿血液。
多因素分析显示，与IHV-FBS组相比，脐带血采样组和心脏穿刺组胎儿丢失的几率增加。仅在心脏穿刺组中，操作后<2周时胎儿丢失具有统计学意义（p<0.01）。
