Student Research Committee, Nursing and Midwifery Faculty, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Medical Ethics and Law Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Taiwan J Obstet Gynecol. 2020 Mar;59(2):173-182. doi: 10.1016/j.tjog.2020.01.002.
Due to the morbidity and mortality of mothers and fetuses developed by preeclampsia, preventive approaches have always been taken into account in high risk individuals. Systematic review studies contribute to make a better decision about the results of such studies. Accordingly, this study strived to systematically study the factors effective in the prevention of preeclampsia. The MEDLINE, ISI Web of Science, PubMed, Scopus, Google Scholar, and Proquest databases were systematically reviewed between January 2000 and May 2019. The quality of the studies was analyzed using the CONSORT checklist. A study was conducted on 29 quality interventional studies; 28 of which were RCT type, and on various factors such as anticoagulants (heparin, enoxaparin, Dalteparin and Nadroparin), aspirin, paravastatin, nitric oxide, yoga, micronutrients Such as l-Arginine, Folic Acid, Vitamin E and C, Phytonutrient, Lycopene and Vitamin D alone or in combination with Calcium. The results of this study showed that low molecular weight heparin, enoxaparin, PETN, yoga, L arginine, folic acid, vitamin D prevented preeclampsia alone or combined with calcium.
由于子痫前期对母亲和胎儿的发病率和死亡率的影响,在高危人群中一直采取预防措施。系统评价研究有助于对这些研究的结果做出更好的决策。因此,本研究旨在系统研究预防子痫前期的有效因素。对 2000 年 1 月至 2019 年 5 月期间 MEDLINE、ISI Web of Science、PubMed、Scopus、Google Scholar 和 Proquest 数据库进行了系统评价。使用 CONSORT 清单分析研究质量。对 29 项高质量的干预性研究进行了研究;其中 28 项为 RCT 类型,研究了抗凝剂(肝素、依诺肝素、达肝素和那屈肝素)、阿司匹林、帕伐他汀、一氧化氮、瑜伽、微量营养素如 L-精氨酸、叶酸、维生素 E 和 C、植物营养素、番茄红素和维生素 D 单独或与钙联合使用等各种因素。这项研究的结果表明,低分子量肝素、依诺肝素、PETN、瑜伽、L 精氨酸、叶酸、维生素 D 单独或与钙联合使用可以预防子痫前期。