Yuliasmi Sri, Ginting Nahitma, Wahyuni Henny Sri, Sigalingging Ruth Theresia, Sibarani Theophani
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Sumatera Utara, Medan 20155, Indonesia.
Open Access Maced J Med Sci. 2019 Nov 14;7(22):3874-3877. doi: 10.3889/oamjms.2019.523. eCollection 2019 Nov 30.
North Sumatra is one of the regions in Indonesia that produce bananas. Banana stems and peels contain cellulose and it can be isolated in nanofiber form. Carboxymethylcellulose is a cellulose derivative that undergoes an alkalization and etherification process.
This research was conducted to evaluate the alkalization effect on synthesis of carboxymethyl cellulose from stem and peel cellulose of banana.
Stem and peel of banana was extracted with NaOH 17.5% and the extract was synthesized to carboxymethyl cellulose (CMC). The synthesis of CMC was beginning with alkalization process in variation of NaOH concentration and the reaction was then etherificated with sodium monochloroacetate. CMC was characterized by FTIR and DS values were determined.
FTIR spectra of synthesized CMC had different pattern compared to cellulose. It showed that an etherification reaction had been occurred in the cellulose compound. Spectra of CMC with variation in alkali concentration was not much different from one another. The synthesized CMC from stem and peel cellulose of banana had different degree of substitution (DS) values due to variate concentration of NaOH in alkalization.
Alkalization on CMC synthesis affects the DS value of synthesized CMC. The increase DS value is proportional to the rise in NaOH concentration even though there is a boundary concentration to obtain the optimum DS value.
北苏门答腊是印度尼西亚生产香蕉的地区之一。香蕉茎和皮含有纤维素，且可以分离成纳米纤维形式。羧甲基纤维素是一种经过碱化和醚化过程的纤维素衍生物。
本研究旨在评估碱化对从香蕉茎和皮纤维素合成羧甲基纤维素的影响。
用17.5%的氢氧化钠提取香蕉的茎和皮，提取物合成羧甲基纤维素（CMC）。CMC的合成从碱化过程开始，改变氢氧化钠浓度，然后用一氯乙酸钠进行醚化反应。通过傅里叶变换红外光谱对CMC进行表征，并测定取代度（DS）值。
合成的CMC的傅里叶变换红外光谱与纤维素相比有不同的图谱。这表明纤维素化合物中发生了醚化反应。不同碱浓度的CMC光谱彼此差异不大。由于碱化过程中氢氧化钠浓度不同，从香蕉茎和皮纤维素合成的CMC具有不同的取代度（DS）值。
CMC合成过程中的碱化影响合成的CMC的DS值。DS值的增加与氢氧化钠浓度的升高成正比，尽管存在一个获得最佳DS值的边界浓度。
