Hillyar Christopher, Nibber Anjan
Medicine and Dentistry, Barts Health NHS Trust, London, GBR.
Neurology, Oxford University Medical School, Oxford University Hospitals NHS Foundation Trust, Oxford, GBR.
Cureus. 2020 Feb 19;12(2):e7051. doi: 10.7759/cureus.7051.
Guillain-Barré syndrome (GBS) is a post-infectious autoimmune polyneuropathy. Recent research has highlighted that GBS is associated with the onset of psychiatric symptoms which represent a burden for patients and close relatives. However, acute psychiatric sequelae due to GBS may be misinterpreted as 'intensive care unit (ICU) delirium'. This review outlines the existing evidence for the psychiatric symptoms associated with GBS with a view to improving psychoeducation of patients. The main psychiatric symptoms of GBS that have been reported in the literature include, stress, anxiety, depression, fatigue, sleep abnormalities, visual hallucinations, paranoid delusions, disorientation, terror and psychosis. These psychiatric symptoms, which occur during the acute phase of GBS, if not recognised and treated, may progress to long-term psychiatric problems that interfere with improvement of physical symptoms. A multidisciplinary team approach to the management of GBS may improve both physical and psychiatric recovery.
格林-巴利综合征（GBS）是一种感染后自身免疫性多发性神经病。最近的研究强调，GBS与精神症状的发作有关，这些症状给患者及其近亲带来了负担。然而，GBS所致的急性精神后遗症可能会被误诊为“重症监护病房（ICU）谵妄”。本综述概述了与GBS相关的精神症状的现有证据，以期改善对患者的心理教育。文献中报道的GBS主要精神症状包括压力、焦虑、抑郁、疲劳、睡眠异常、视幻觉、偏执妄想、定向障碍、恐惧和精神病。这些在GBS急性期出现的精神症状，如果未被识别和治疗，可能会发展为长期精神问题，从而妨碍身体症状的改善。采用多学科团队方法管理GBS可能会促进身体和精神的康复。
